From neuron to behavior: Sensory-motor coordination of zebrafish turning behavior

Keiko Umeda, Wataru Shoji

Research output: Contribution to journalReview article

6 Citations (Scopus)

Abstract

Recent development of optogenetics brought non-invasive neural activation in living organisms. Transparent zebrafish larva is one of the suitable animal models for this technique, which enables us to investigate neural circuits for behaviors based on a whole individual nervous system. In this article we review our recent finding that suggests sensory-motor coordination in larval zebrafish escape behavior. When water vibration stimulates mechanosensory Rohon-Beard (RB) neurons, intra-spinal reflex circuit launches contralateral trunk muscle contraction that makes rapid body curvature for turning. In addition, positional information of the stimulus is conveyed to supra-spinal circuits, and then regulates the curvature strength for appropriate escape pathway from the threat. Sensory-motor coordination is a fundamental feature to adapt behaviors to environment, and zebrafish larvae would be an excellent model for elucidating its neural backbones.

Original languageEnglish
Pages (from-to)107-114
Number of pages8
JournalDevelopment Growth and Differentiation
Volume59
Issue number3
DOIs
Publication statusPublished - 2017 Apr

Keywords

  • Channelrhodopsin
  • Rohon-Beard neuron
  • escape behavior
  • optogenetics
  • zebrafish

ASJC Scopus subject areas

  • Developmental Biology
  • Cell Biology

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