Frequency of amantadine-resistant influenza A viruses during two seasons featuring cocirculation of H1N1 and H3N2

Reiko Saito, Takatsugu Sakai, Isamu Sato, Yasuko Sano, Hitoshi Oshitani, Mizuho Sato, Hiroshi Suzuki

Research output: Contribution to journalArticle

59 Citations (Scopus)

Abstract

In two influenza seasons during which H1N1 and H3N2 cocirculated, resistance was more frequent in H3N2 strains than in H1N1 strains after amantadine treatment. Predominant amino acid substitutions in M2 protein occurred at position 31 (serine to asparagine) in H3N2 strains and at position 27 (valine to alanine) in H1N1 strains.

Original languageEnglish
Pages (from-to)2164-2165
Number of pages2
JournalJournal of Clinical Microbiology
Volume41
Issue number5
DOIs
Publication statusPublished - 2003 May 1

ASJC Scopus subject areas

  • Microbiology (medical)

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