To acquire images of dynamic scenes from multiple points of view simultaneously, the acquisition time of vision sensors should be synchronized. Although the influences of background light and the amplitude fluctuation have been successfully eliminated, it is still necessary to distinguish the frame indexes of multiple synchronized vision sensors. In this paper, an illumination-based synchronization derived from the phase-locked loop (PLL) mechanism based on the Manchester Encoding technique is proposed and evaluated. The blinking illumination signal can carry the sequential information by being arbitrarily modulated as pseudo random sequence. Simulated results demonstrated the successful synchronization result that 1,000-Hz frame rate vision sensors can be successfully synchronized to a LED illumination modulated to be 250 Hz with satisfactory stability and jitters.