Formation of DNA micro-skeleton structures in water-in-oil microdroplets

Masamune Morita, Shin Ichiro M. Nomura, Satoshi Murata, Miho Yanagisawa, Masahiro Takinoue

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We show a novel DNA microstructure, named “DNA micro-skeleton”. This DNA microstructure is constructed by self-assembly of Y-motif DNA inside water-in-oil microdroplets covered with cationic lipids. The DNA micro-skeleton is a porous and hollow microcapsule with a large surface area. Therefore, we believe the structure will have potentials for physical and biomedical use such as artificial cells and molecular robots, which will be realized by the advantage of the soft but robust structure and also its large surface area.

Original languageEnglish
Title of host publication21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017
PublisherChemical and Biological Microsystems Society
Pages159-160
Number of pages2
ISBN (Electronic)9780692941836
Publication statusPublished - 2020 Jan 1
Event21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017 - Savannah, United States
Duration: 2017 Oct 222017 Oct 26

Publication series

Name21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017

Conference

Conference21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017
CountryUnited States
CitySavannah
Period17/10/2217/10/26

Keywords

  • DNA hydrogel
  • DNA nanotechnology
  • Self-assembly
  • Water-in-oil droplets

ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Bioengineering

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  • Cite this

    Morita, M., Nomura, S. I. M., Murata, S., Yanagisawa, M., & Takinoue, M. (2020). Formation of DNA micro-skeleton structures in water-in-oil microdroplets. In 21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017 (pp. 159-160). (21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017). Chemical and Biological Microsystems Society.