Abstract
Polyethylene terephthalate (PET), ethylene-vinyl alcohol copolymer (EVOH) and Nylon 6 in plate form were treated with silane-coupling agents, a titanium alkoxide-alcohol solution and a hot HCl solution to form a thin crystalline titanium oxide layer. When placed in a simulated body fluid with ion concentrations nearly equal to those of the human blood plasma, nanosized bone-like apatite formed uniformly on the surfaces of these treated polymers: within 2 days for PET and Nylon 6, and 7 days for EVOH. This indicates that such titania-modified polymers might form bone-like apatite in the living body, and bond to living bone through this apatite layer. Three-dimensional fabrics of these polymer fibers, with open spaces in various sizes, are expected to be useful as bone substitutes, as they will be integrated with the natural bone.
Original language | English |
---|---|
Pages (from-to) | 1704-1710 |
Number of pages | 7 |
Journal | Biomaterials |
Volume | 27 |
Issue number | 9 |
DOIs | |
Publication status | Published - 2006 Mar |
Keywords
- Apatite
- Bioactive materials
- Polyethylene terephthalate
- Surface modification
- Titanium oxide
ASJC Scopus subject areas
- Bioengineering
- Ceramics and Composites
- Biophysics
- Biomaterials
- Mechanics of Materials