Folding of dihelicenetriamines in water

Shinobu Honzawa, Hitoshi Okubo, Keiichi Nakamura, Shuzo Anzai, Masahiko Yamaguchi, Chizuko Kabuto

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)


Diastereomeric triamines containing two helicene moieties, 1,12-dimethylbenzo[c]phenanthrene, were synthesized and found to form folded structures in the water. Such folding was not observed for an achiral compound possessing a naphthalene moiety. The (M,M)-dihelicenetriamine with matching configuration at the helicene moieties formed a more stable folded structure than the (P,M)-isomer containing two enantiomeric helicene groups. The most stable folded conformation was predicted by the Monte Carlo method with Amber force field of the dihelicenetriamine.

Original languageEnglish
Pages (from-to)1043-1052
Number of pages10
JournalTetrahedron Asymmetry
Issue number10
Publication statusPublished - 2002 Jun 10

ASJC Scopus subject areas

  • Catalysis
  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry


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