Fluorescent genipin cross-linked REDV-conjugated polymeric microbubbles for human vascular endothelial cell (HVEC) targeting

Zhe Liu, Changcan Shi, Yihong Li, Yuanhui Song, Qien Xu

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Polymeric microbubbles modified with chitosan and genipin were fabricated via emulsification, electrostatic interaction and cross-linking to afford intrinsic fluorescence. REDV peptides were conjugated to achieve HVEC active targeting. The degradation, cytotoxicity and targeting features made them potential candidates in early molecular diagnosis for cardiovascular diseases.

Original languageEnglish
Pages (from-to)32710-32714
Number of pages5
JournalRSC Advances
Volume6
Issue number39
DOIs
Publication statusPublished - 2016

ASJC Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)

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