Fluorescence detection of guanine-adenine transition by a hydrogen bond forming small compound

Keitaro Yoshimoto, Chun Yan Xu, Seiichi Nishizawa, Takanobu Haga, Hiroyuki Satake, Norio Teramae

Research output: Contribution to journalArticlepeer-review

50 Citations (Scopus)

Abstract

In combination with abasic site-containing oligodeoxynucleotides, 2-amino-4-oxopteridine (pterin) can selectively recognize guanine base over other nucleobases accompanied by fluorescence quenching, which allows clear detection of a guanine-adenine transition with the naked eye.

Original languageEnglish
Pages (from-to)2960-2961
Number of pages2
JournalChemical Communications
Volume3
Issue number24
DOIs
Publication statusPublished - 2003 Jan 1

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

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