Fluctuations in antibody titers against enterovirus D68 in pediatric sera collected in a community before, during, and after a possible outbreak

Francois Marie Ngako Kadji, Hidekazu Nishimura, Michiko Okamoto, Ko Sato, Suguru Ohmiya, Hiroko Ito, Akira Suzuki, Yukio Nagai, Hitoshi Oshitani

Research output: Contribution to journalShort surveypeer-review

1 Citation (Scopus)

Abstract

We previously reported a hospital-based epidemiological study on enterovirus (EV)-D68 infection among children during the autumn of 2015, which indirectly inferred an outbreak in Sendai, Japan. In this study, stocked sera of children (aged 0–6 years; without symptoms of infectious diseases) in the Sendai community collected during 4 periods (1 year before, 6 months before, immediately after, and 1 year after the possible outbreak period) were analyzed using the neutralization antibody titer assay to determine community children’s immunity levels against EV-D68 infection. The immunity levels were confirmed to have increased during the possible outbreak period and to have gradually waned over 1 year without another outbreak. These results provide background information supporting the results of our previous hospital-based surveillance study.

Original languageEnglish
Pages (from-to)55-57
Number of pages3
JournalJapanese journal of infectious diseases
Volume73
Issue number1
DOIs
Publication statusPublished - 2020

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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