Five-year survivors with resected pN2 nonsmall cell lung carcinoma

Motoyasu Sagawa, Akira Sakurada, Shigefumi Fujimura, Masami Sato, Satomi Takahashi, Katsuo Usuda, Chiaki Endo, Hirokazu Aikawa, Takashi Kondo, Yasuki Saito

Research output: Contribution to journalArticlepeer-review

32 Citations (Scopus)

Abstract

BACKGROUND. Some patients with resected pN2 lung carcinoma were long term survivors. To determine appropriate therapeutic modalities for the selected patients, the clinicopathologic characteristics of these patients were examined using the actual number of survivors rather than the cumulative survival rate because the cumulative survival rate occasionally is confounded due to patients with short follow-up periods. METHODS. Between 1981-1990, 178 patients with pN2 nonsmall cell lung carcinoma underwent complete resection with systemic lymph node dissection. The ratios of 5-year survivors to all patients in groups with several clinicopathologic factors were compared. RESULTS. Gender, the side that was operated on, location of the tumor, histologic type, or surgical procedure were not related to the ratio of 5- year survivors. However, T classification, skip metastasis, and the number of levels involved were associated with the ratio significantly. The authors also found that the location of the involved lymph node(s) affected the ratio. Conclusions. Even in the presence of pN2 disease, lung carcinoma patients with T1 tumors, skip metastasis, or single level mediastinal lymph node involvement, especially Level 4, Level 5, or Level 6 lymph nodes, had a relatively favorable prognosis and may be candidates for primary resection.

Original languageEnglish
Pages (from-to)864-868
Number of pages5
JournalCancer
Volume85
Issue number4
DOIs
Publication statusPublished - 1999 Feb 15

Keywords

  • 5-year survivor
  • Lung carcinoma
  • N2 disease
  • Pregnosis
  • Surgical therapy

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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