Fish oil and omega-3 fatty acids in cardiovascular disease: Do they really work?

Daan Kromhout, Satoshi Yasuda, Johanna M. Geleijnse, Hiroaki Shimokawa

Research output: Contribution to journalReview articlepeer-review

141 Citations (Scopus)

Abstract

Omega-3 fatty acids, which are found abundantly in fish oil, exert pleiotropic cardiometabolic effects with a diverse range of actions. The results of previous studies raised a lot of interest in the role of fish oil and omega-3 fatty acids in primary and secondary prevention of cardiovascular diseases. The present review will focus on the current clinical uses of omega-3 fatty acids and provide an update on their effects. Since recently published trials in patients with coronary artery diseases or post-myocardial infarction did not show an effect of omega-3 fatty acids on major cardiovascular endpoints, this review will examine the limitations of those data and suggest recommendations for the use of omega-3 fatty acids.

Original languageEnglish
Pages (from-to)436-443
Number of pages8
JournalEuropean Heart Journal
Volume33
Issue number4
DOIs
Publication statusPublished - 2012 Feb

Keywords

  • Cardiovascular disease
  • Fish oils

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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