Fine structure of calcitonin gene-related peptide-immunoreactive nerve fibres in the rat temporomandibular joint

H. Ichikawa, S. Matsuo, S. Wakisaka, M. Akai

Research output: Contribution to journalArticlepeer-review

24 Citations (Scopus)

Abstract

The distribution and fine structure of these nerve fibres was examined by immunoelectron microscopy. CGRP-immunoreactive fibres were seen in the nerve bundles, blood vessels and periosteum around the condyle as well as in the disc. These nerve fibres were unmyelinated and had diameters varying from 200 to 600 nm. They were completely or partially enclosed by Schwann cell cytoplasm and did not form synaptic contact with any cells. CGRP-immunoreactive nerve fibres may be of sensory nature and this peptide could be involved in pain transmission and neurogenic inflammation.

Original languageEnglish
Pages (from-to)727-730
Number of pages4
JournalArchives of Oral Biology
Volume35
Issue number9
DOIs
Publication statusPublished - 1990
Externally publishedYes

Keywords

  • calcitonin gene-related peptide
  • nerve
  • neuropeptide
  • rat
  • temporomandibular joint

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Dentistry(all)
  • Cell Biology

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