Fibroblasts culture on polyacrylamide hydrogels with functional gradient

Kaoru Yanase, Masaya Yamamoto, Yasuhiko Tabata

Research output: Contribution to conferencePaperpeer-review


It is well known that complex multicellular process of tissue development and regeneration is generally regulated by the spatial arrangement of matrix and signal molecules in a time- and concentration-dependent manner. Based on the natural morphogenic process, various cell scaffolds of three-dimension have been designed to mimic the natural extracellular microenvironments that enable cells to regulate tissue regeneration. In this study, a polyacrylamide hydrogel scaffold with a spatial gradient of functional group has been explored to investigate the adhesion and proliferation of fibroblasts on the scaffold.

Original languageEnglish
Number of pages1
Publication statusPublished - 2005
Externally publishedYes
Event54th SPSJ Annual Meeting 2005 - Yokohama, Japan
Duration: 2005 May 252005 May 27


Other54th SPSJ Annual Meeting 2005


  • Functional gradient
  • Polyacrylamide hydrogel scaffold

ASJC Scopus subject areas

  • Engineering(all)


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