TY - JOUR
T1 - Fiber-based polarization-sensitive OCT for birefringence imaging of the anterior eye segment
AU - Yamanari, Masahiro
AU - Tsuda, Satoru
AU - Kokubun, Taiki
AU - Shiga, Yukihiro
AU - Omodaka, Kazuko
AU - Yokoyama, Yu
AU - Himori, Noriko
AU - Ryu, Morin
AU - Kunimatsu-Sanuki, Shiho
AU - Takahashi, Hidetoshi
AU - Maruyama, Kazuichi
AU - Kunikata, Hiroshi
AU - Nakazawa, Toru
N1 - Publisher Copyright:
© 2015 Optical Society of America.
PY - 2015
Y1 - 2015
N2 - We demonstrate a prototype system of polarization-sensitive optical coherence tomography (PS-OCT) designed for clinical studies of the anterior eye segment imaging. The system can measure Jones matrices of the sample with depth-multiplexing of two orthogonal incident polarizations and polarization-sensitive detection. An optical clock is generated using a quadrature modulator and a logical circuit to double the clock frequency. Systematic artifacts in measured Jones matrices are theoretically analyzed and numerically compensated using signals at the surface of the sample. Local retardation images of filtering blebs after trabeculectomy show improved visualization of subconjunctival tissue, sclera, and scar tissue of the bleb wall in the anterior eye segment.
AB - We demonstrate a prototype system of polarization-sensitive optical coherence tomography (PS-OCT) designed for clinical studies of the anterior eye segment imaging. The system can measure Jones matrices of the sample with depth-multiplexing of two orthogonal incident polarizations and polarization-sensitive detection. An optical clock is generated using a quadrature modulator and a logical circuit to double the clock frequency. Systematic artifacts in measured Jones matrices are theoretically analyzed and numerically compensated using signals at the surface of the sample. Local retardation images of filtering blebs after trabeculectomy show improved visualization of subconjunctival tissue, sclera, and scar tissue of the bleb wall in the anterior eye segment.
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U2 - 10.1364/BOE.6.000369
DO - 10.1364/BOE.6.000369
M3 - Article
AN - SCOPUS:84942370813
VL - 6
SP - 369
EP - 389
JO - Biomedical Optics Express
JF - Biomedical Optics Express
SN - 2156-7085
IS - 2
ER -