Fiber-Assisted Molding (FAM) of surfaces with tunable curvature to guide cell alignment and complex tissue architecture

Vahid Hosseini, Philip Kollmannsberger, Samad Ahadian, Serge Ostrovidov, Hirokazu Kaji, Viola Vogel, Ali Khademhosseini

Research output: Contribution to journalArticlepeer-review

32 Citations (Scopus)

Abstract

A simple and robust method termed "fiber-assisted molding (FAM)" is presented to create biomimetic three-dimensional surfaces with controllable curvature and helical twist. The alignment of muscle fibrils and the assembly of helically patterned extracellular matrix by cells demonstrate the potential of this method for tissue engineering and other materials science applications.

Original languageEnglish
Pages (from-to)4851-4857
Number of pages7
JournalSmall
Volume10
Issue number23
DOIs
Publication statusPublished - 2014 Dec 10

Keywords

  • Cell alignment
  • Curvature
  • Fibers
  • Microfabrication
  • Tissue engineering

ASJC Scopus subject areas

  • Biotechnology
  • Biomaterials
  • Chemistry(all)
  • Materials Science(all)

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