Fate of Homograft Cartilage Implanted in the Middle Ear

Etsuo Yamamoto, Michitaka Iwanaga, Manabu Fukumoto

Research output: Contribution to journalArticlepeer-review


In a study of the fate of homograft cartilages implanted into the middle ear, the transplanted cartilages removed at revision surgery or at the second stage of staged tympanoplasty were examined histologically. The appearance and shape of the cartilages remained unchanged without any evidence of erosion. There was no foreign body reaction or rejection phenomenon. No marked changes were seen in the matrix, but the chondrocytes showed degenerative changes. There was partial absorption of the cartilage and replacement by fibrous tissue when inflammatory changes were present in the middle ear. It is concluded that implanted homograft cartilage can be expected to maintain its stiffness for a long time in healthy, aerated middle ears.

Original languageEnglish
Pages (from-to)1103-1111
Number of pages9
JournalPractica Oto-Rhino-Laryngologica
Issue number6
Publication statusPublished - 1985
Externally publishedYes

ASJC Scopus subject areas

  • Otorhinolaryngology


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