Familial pure akinesia

H. Narai, Y. Manabe, T. Murakami, Hitoshi Warita, K. Abe

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

We report a 67-year-old man and his family presenting pure akinesia (PA). He developed bradykinesia. A neurological examination showed a lack of facial expression but no tremor or rigidity. His eye movement was full, and he had frozen gait and pulsion symptoms. There was no evidence of dementia. Levodopa therapy was not effective. Magnetic resonance imaging revealed no brainstem and cerebellar atrophy. 99mTc-ECD-SPECT had no further abnormality. His father and brother had similar symptoms as him. We conclude that this family is the first reported example of pure akinesia with autosomal dominant inheritance.

Original languageEnglish
Pages (from-to)1101-1104
Number of pages4
JournalClinical Neurology
Volume40
Issue number11
Publication statusPublished - 2000 Dec 1
Externally publishedYes

Keywords

  • Autosomal dominant inheritance
  • Familial parkinsonism
  • Pure akinesia

ASJC Scopus subject areas

  • Clinical Neurology

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