False-positive human immunodeficiency virus antibody test and autoimmune hemolytic anemia in a patient with angioimmunoblastic T-cell lymphoma

Seiji Shida, Naoto Takahashi, Naohito Fujishima, Yoshihiro Kameoka, Miho Nara, Masumi Fujishima, Hirobumi Saitoh, Hiroyuki Tagawa, Makoto Hirokawa, Ryo Ichinohasama, Kenichi Sawada

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

A 44-year-old woman was admitted with generalized lymphadenopathy, which was diagnosed as angioimmunoblastic T-cell lymphoma (AITL). The patient showed autoimmune hemolytic anemia (AIHA), polyclonal hypergammaglobulinemia and a high antinuclear antibody titer. Moreover, a human immunodeficiency virus (HIV)-1/2 screening test using the particle agglutination method was reactive. After chemotherapy for AITL, the AIHA was eliminated, and the false-positive HIV results were no longer detected. Autoimmunity associated with AITL is the likely cause of the cross-reaction with HIV and the AIHA. It is important to recognize that the cross-reaction with HIV can be a potential complication in AITL as well as AIHA.

Original languageEnglish
Pages (from-to)2383-2387
Number of pages5
JournalInternal Medicine
Volume50
Issue number20
DOIs
Publication statusPublished - 2011

Keywords

  • Angioimmunoblastic T-cell lymphoma
  • Autoimmune hemolytic anemia
  • Human immunodeficiency virus

ASJC Scopus subject areas

  • Internal Medicine

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