Factors influencing pulmonary surfactant protein A levels in cord blood, maternal blood and amniotic fluid

Kazutoshi Cho; Tadashi Matsuda; Satoru Okajima; Yoshinori Matsumoto; Tadashi Sagawa; Seiichiro Fujimoto; Kunihiko Kobayashi

doi:10.1159/000014085

Factors influencing pulmonary surfactant protein A levels in cord blood, maternal blood and amniotic fluid

Kazutoshi Cho, Tadashi Matsuda, Satoru Okajima, Yoshinori Matsumoto, Tadashi Sagawa, Seiichiro Fujimoto, Kunihiko Kobayashi

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Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Abstract

The purpose of this study was to evaluate factors that influence pulmonary surfactant protein A (SP-A) levels in cord blood, maternal blood and amniotic fluid, as well as to establish the normal range of serum SP-A. Labor significantly influenced cord blood SPA levels. The SP-A levels in maternal blood after delivery were correlated with, but higher than those before delivery. There was a correlation between SP-A levels in amniotic fluid and cord blood. Neonatal serum SP-A was not correlated with maternal SP-A levels. The normal range of SP-A in cord blood was 2.7-21.7 ng/ml following cesarean section without labor, 4.8-50.2 ng/ml after labor at gestational weeks 36-38, and 12.2-44.6 ng/ml at gestational weeks 39-41. SP-A levels in maternal blood before and after delivery and amniotic fluid were 6.0-74.0, 9.6-73.6 and 403.4-24,540 ng/ml, respectively.

Original language	English
Pages (from-to)	104-110
Number of pages	7
Journal	Biology of the Neonate
Volume	75
Issue number	2
DOIs	https://doi.org/10.1159/000014085
Publication status	Published - 1999 Feb

Keywords

Amniotic fluid
Cord blood
Maternal blood
Pulmonary surfactant protein A, normal range

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Developmental Biology

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10.1159/000014085

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Factors influencing pulmonary surfactant protein A levels in cord blood, maternal blood and amniotic fluid. / Cho, Kazutoshi; Matsuda, Tadashi; Okajima, Satoru; Matsumoto, Yoshinori; Sagawa, Tadashi; Fujimoto, Seiichiro; Kobayashi, Kunihiko.

In: Biology of the Neonate, Vol. 75, No. 2, 02.1999, p. 104-110.

Research output: Contribution to journal › Article › peer-review

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