TY - JOUR
T1 - Factors influencing pulmonary surfactant protein A levels in cord blood, maternal blood and amniotic fluid
AU - Cho, Kazutoshi
AU - Matsuda, Tadashi
AU - Okajima, Satoru
AU - Matsumoto, Yoshinori
AU - Sagawa, Tadashi
AU - Fujimoto, Seiichiro
AU - Kobayashi, Kunihiko
PY - 1999/2
Y1 - 1999/2
N2 - The purpose of this study was to evaluate factors that influence pulmonary surfactant protein A (SP-A) levels in cord blood, maternal blood and amniotic fluid, as well as to establish the normal range of serum SP-A. Labor significantly influenced cord blood SPA levels. The SP-A levels in maternal blood after delivery were correlated with, but higher than those before delivery. There was a correlation between SP-A levels in amniotic fluid and cord blood. Neonatal serum SP-A was not correlated with maternal SP-A levels. The normal range of SP-A in cord blood was 2.7-21.7 ng/ml following cesarean section without labor, 4.8-50.2 ng/ml after labor at gestational weeks 36-38, and 12.2-44.6 ng/ml at gestational weeks 39-41. SP-A levels in maternal blood before and after delivery and amniotic fluid were 6.0-74.0, 9.6-73.6 and 403.4-24,540 ng/ml, respectively.
AB - The purpose of this study was to evaluate factors that influence pulmonary surfactant protein A (SP-A) levels in cord blood, maternal blood and amniotic fluid, as well as to establish the normal range of serum SP-A. Labor significantly influenced cord blood SPA levels. The SP-A levels in maternal blood after delivery were correlated with, but higher than those before delivery. There was a correlation between SP-A levels in amniotic fluid and cord blood. Neonatal serum SP-A was not correlated with maternal SP-A levels. The normal range of SP-A in cord blood was 2.7-21.7 ng/ml following cesarean section without labor, 4.8-50.2 ng/ml after labor at gestational weeks 36-38, and 12.2-44.6 ng/ml at gestational weeks 39-41. SP-A levels in maternal blood before and after delivery and amniotic fluid were 6.0-74.0, 9.6-73.6 and 403.4-24,540 ng/ml, respectively.
KW - Amniotic fluid
KW - Cord blood
KW - Maternal blood
KW - Pulmonary surfactant protein A, normal range
UR - http://www.scopus.com/inward/record.url?scp=0032952002&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0032952002&partnerID=8YFLogxK
U2 - 10.1159/000014085
DO - 10.1159/000014085
M3 - Article
C2 - 9852361
AN - SCOPUS:0032952002
VL - 75
SP - 104
EP - 110
JO - Neonatology
JF - Neonatology
SN - 1661-7800
IS - 2
ER -