Factors influencing pulmonary surfactant protein A levels in cord blood, maternal blood and amniotic fluid

Kazutoshi Cho; Tadashi Matsuda; Satoru Okajima; Yoshinori Matsumoto; Tadashi Sagawa; Seiichiro Fujimoto; Kunihiko Kobayashi

doi:10.1159/000014085

Factors influencing pulmonary surfactant protein A levels in cord blood, maternal blood and amniotic fluid

Kazutoshi Cho, Tadashi Matsuda, Satoru Okajima, Yoshinori Matsumoto, Tadashi Sagawa, Seiichiro Fujimoto, Kunihiko Kobayashi

Special Clinical Facilities

Research output: Contribution to journal › Article

13 Citations (Scopus)

Abstract

The purpose of this study was to evaluate factors that influence pulmonary surfactant protein A (SP-A) levels in cord blood, maternal blood and amniotic fluid, as well as to establish the normal range of serum SP-A. Labor significantly influenced cord blood SPA levels. The SP-A levels in maternal blood after delivery were correlated with, but higher than those before delivery. There was a correlation between SP-A levels in amniotic fluid and cord blood. Neonatal serum SP-A was not correlated with maternal SP-A levels. The normal range of SP-A in cord blood was 2.7-21.7 ng/ml following cesarean section without labor, 4.8-50.2 ng/ml after labor at gestational weeks 36-38, and 12.2-44.6 ng/ml at gestational weeks 39-41. SP-A levels in maternal blood before and after delivery and amniotic fluid were 6.0-74.0, 9.6-73.6 and 403.4-24,540 ng/ml, respectively.

Original language	English
Pages (from-to)	104-110
Number of pages	7
Journal	Biology of the Neonate
Volume	75
Issue number	2
DOIs	https://doi.org/10.1159/000014085
Publication status	Published - 1999 Feb

Keywords

Amniotic fluid
Cord blood
Maternal blood
Pulmonary surfactant protein A, normal range

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Developmental Biology

Access to Document

10.1159/000014085

Fingerprint Dive into the research topics of 'Factors influencing pulmonary surfactant protein A levels in cord blood, maternal blood and amniotic fluid'. Together they form a unique fingerprint.

Cite this

Cho, K., Matsuda, T., Okajima, S., Matsumoto, Y., Sagawa, T., Fujimoto, S., & Kobayashi, K. (1999). Factors influencing pulmonary surfactant protein A levels in cord blood, maternal blood and amniotic fluid. Biology of the Neonate, 75(2), 104-110. https://doi.org/10.1159/000014085

@article{f2eaae98f9b44cc494541e6ec20f4e22,

title = "Factors influencing pulmonary surfactant protein A levels in cord blood, maternal blood and amniotic fluid",

abstract = "The purpose of this study was to evaluate factors that influence pulmonary surfactant protein A (SP-A) levels in cord blood, maternal blood and amniotic fluid, as well as to establish the normal range of serum SP-A. Labor significantly influenced cord blood SPA levels. The SP-A levels in maternal blood after delivery were correlated with, but higher than those before delivery. There was a correlation between SP-A levels in amniotic fluid and cord blood. Neonatal serum SP-A was not correlated with maternal SP-A levels. The normal range of SP-A in cord blood was 2.7-21.7 ng/ml following cesarean section without labor, 4.8-50.2 ng/ml after labor at gestational weeks 36-38, and 12.2-44.6 ng/ml at gestational weeks 39-41. SP-A levels in maternal blood before and after delivery and amniotic fluid were 6.0-74.0, 9.6-73.6 and 403.4-24,540 ng/ml, respectively.",

keywords = "Amniotic fluid, Cord blood, Maternal blood, Pulmonary surfactant protein A, normal range",

author = "Kazutoshi Cho and Tadashi Matsuda and Satoru Okajima and Yoshinori Matsumoto and Tadashi Sagawa and Seiichiro Fujimoto and Kunihiko Kobayashi",

year = "1999",

month = feb,

doi = "10.1159/000014085",

language = "English",

volume = "75",

pages = "104--110",

journal = "Neonatology",

issn = "1661-7800",

publisher = "S. Karger AG",

number = "2",

}

TY - JOUR

T1 - Factors influencing pulmonary surfactant protein A levels in cord blood, maternal blood and amniotic fluid

AU - Cho, Kazutoshi

AU - Matsuda, Tadashi

AU - Okajima, Satoru

AU - Matsumoto, Yoshinori

AU - Sagawa, Tadashi

AU - Fujimoto, Seiichiro

AU - Kobayashi, Kunihiko

PY - 1999/2

Y1 - 1999/2

N2 - The purpose of this study was to evaluate factors that influence pulmonary surfactant protein A (SP-A) levels in cord blood, maternal blood and amniotic fluid, as well as to establish the normal range of serum SP-A. Labor significantly influenced cord blood SPA levels. The SP-A levels in maternal blood after delivery were correlated with, but higher than those before delivery. There was a correlation between SP-A levels in amniotic fluid and cord blood. Neonatal serum SP-A was not correlated with maternal SP-A levels. The normal range of SP-A in cord blood was 2.7-21.7 ng/ml following cesarean section without labor, 4.8-50.2 ng/ml after labor at gestational weeks 36-38, and 12.2-44.6 ng/ml at gestational weeks 39-41. SP-A levels in maternal blood before and after delivery and amniotic fluid were 6.0-74.0, 9.6-73.6 and 403.4-24,540 ng/ml, respectively.

AB - The purpose of this study was to evaluate factors that influence pulmonary surfactant protein A (SP-A) levels in cord blood, maternal blood and amniotic fluid, as well as to establish the normal range of serum SP-A. Labor significantly influenced cord blood SPA levels. The SP-A levels in maternal blood after delivery were correlated with, but higher than those before delivery. There was a correlation between SP-A levels in amniotic fluid and cord blood. Neonatal serum SP-A was not correlated with maternal SP-A levels. The normal range of SP-A in cord blood was 2.7-21.7 ng/ml following cesarean section without labor, 4.8-50.2 ng/ml after labor at gestational weeks 36-38, and 12.2-44.6 ng/ml at gestational weeks 39-41. SP-A levels in maternal blood before and after delivery and amniotic fluid were 6.0-74.0, 9.6-73.6 and 403.4-24,540 ng/ml, respectively.

KW - Amniotic fluid

KW - Cord blood

KW - Maternal blood

KW - Pulmonary surfactant protein A, normal range

UR - http://www.scopus.com/inward/record.url?scp=0032952002&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032952002&partnerID=8YFLogxK

U2 - 10.1159/000014085

DO - 10.1159/000014085

M3 - Article

C2 - 9852361

AN - SCOPUS:0032952002

VL - 75

SP - 104

EP - 110

JO - Neonatology

JF - Neonatology

SN - 1661-7800

IS - 2

ER -