Facile synthesis of oligosaccharide-poly(L-lactide) conjugates forming nanoparticles with saccharide core and shell

Tomonari Tanaka; Hiroyuki Fukuhara; Shin Ichiro Shoda; Yoshiharu Kimura

doi:10.1246/cl.2013.197

Facile synthesis of oligosaccharide-poly(L-lactide) conjugates forming nanoparticles with saccharide core and shell

Tomonari Tanaka, Hiroyuki Fukuhara, Shin Ichiro Shoda, Yoshiharu Kimura

ENG - Biomolecular Engineering

Research output: Contribution to journal › Article

4 Citations (Scopus)

Abstract

Various oligosaccharidepoly(L-lactide) conjugates (Sac-PLLAs) were synthesized readily through the direct azidation of unprotected saccharides followed by click chemistry with acetylene-terminated poly(L-lactide)s. The Sac-PLLAs were found to form aggregates with the saccharide moieties as the core and shell in nonpolar and polar solvents, respectively.

Original language	English
Pages (from-to)	197-199
Number of pages	3
Journal	Chemistry Letters
Volume	42
Issue number	2
DOIs	https://doi.org/10.1246/cl.2013.197
Publication status	Published - 2013 Feb 21

ASJC Scopus subject areas

Chemistry(all)

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abstract = "Various oligosaccharidepoly(L-lactide) conjugates (Sac-PLLAs) were synthesized readily through the direct azidation of unprotected saccharides followed by click chemistry with acetylene-terminated poly(L-lactide)s. The Sac-PLLAs were found to form aggregates with the saccharide moieties as the core and shell in nonpolar and polar solvents, respectively.",

author = "Tomonari Tanaka and Hiroyuki Fukuhara and Shoda, {Shin Ichiro} and Yoshiharu Kimura",

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AU - Kimura, Yoshiharu

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AB - Various oligosaccharidepoly(L-lactide) conjugates (Sac-PLLAs) were synthesized readily through the direct azidation of unprotected saccharides followed by click chemistry with acetylene-terminated poly(L-lactide)s. The Sac-PLLAs were found to form aggregates with the saccharide moieties as the core and shell in nonpolar and polar solvents, respectively.

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