Facile synthesis of 3,4-diiododihydrothiophenes via electrophilic iodocyclization

Fan Yang; Tienan Jin; Ming Bao; Yoshinori Yamamoto

doi:10.1016/j.tetlet.2010.12.075

Facile synthesis of 3,4-diiododihydrothiophenes via electrophilic iodocyclization

Fan Yang, Tienan Jin, Ming Bao, Yoshinori Yamamoto

SCI - Research and Analytical Center for Giant Molecules

Research output: Contribution to journal › Article › peer-review

24 Citations (Scopus)

Abstract

A facile, efficient, and general synthetic method for the construction of 3,4-diiododihydrothiophenes has been developed via the electrophilic iodocyclization of various S-hydroxy-2-butynyl ethanethioates. Application of the resulting iodine-containing products in organic transformations has been investigated.

Original language	English
Pages (from-to)	936-938
Number of pages	3
Journal	Tetrahedron Letters
Volume	52
Issue number	8
DOIs	https://doi.org/10.1016/j.tetlet.2010.12.075
Publication status	Published - 2011 Feb 23

Keywords

3,4-Diiododihydrothiophenes
Iodine
Iodocyclization
S-4-Hydroxy-2-butynyl ethanethioates

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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abstract = "A facile, efficient, and general synthetic method for the construction of 3,4-diiododihydrothiophenes has been developed via the electrophilic iodocyclization of various S-hydroxy-2-butynyl ethanethioates. Application of the resulting iodine-containing products in organic transformations has been investigated.",

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AU - Yang, Fan

AU - Jin, Tienan

AU - Bao, Ming

AU - Yamamoto, Yoshinori

PY - 2011/2/23

Y1 - 2011/2/23

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AB - A facile, efficient, and general synthetic method for the construction of 3,4-diiododihydrothiophenes has been developed via the electrophilic iodocyclization of various S-hydroxy-2-butynyl ethanethioates. Application of the resulting iodine-containing products in organic transformations has been investigated.

KW - 3,4-Diiododihydrothiophenes

KW - Iodine

KW - Iodocyclization

KW - S-4-Hydroxy-2-butynyl ethanethioates

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