Facile synthesis of 3,4-diiododihydrothiophenes via electrophilic iodocyclization

Fan Yang, Tienan Jin, Ming Bao, Yoshinori Yamamoto

Research output: Contribution to journalArticlepeer-review

24 Citations (Scopus)

Abstract

A facile, efficient, and general synthetic method for the construction of 3,4-diiododihydrothiophenes has been developed via the electrophilic iodocyclization of various S-hydroxy-2-butynyl ethanethioates. Application of the resulting iodine-containing products in organic transformations has been investigated.

Original languageEnglish
Pages (from-to)936-938
Number of pages3
JournalTetrahedron Letters
Volume52
Issue number8
DOIs
Publication statusPublished - 2011 Feb 23

Keywords

  • 3,4-Diiododihydrothiophenes
  • Iodine
  • Iodocyclization
  • S-4-Hydroxy-2-butynyl ethanethioates

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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