TY - JOUR
T1 - Fabrication of porous blocks of calcium phosphate through hydrothermal processing under glycine coexistence
AU - Kawachi, Giichiro
AU - Misumi, Hidetoshi
AU - Fujimori, Hirotaka
AU - Goto, Seishi
AU - Ohtsuki, Chikara
AU - Kamitakahara, Masanobu
AU - Ioku, Koji
N1 - Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 2010/7
Y1 - 2010/7
N2 - Porous hydroxyapatite (HA) and beta-tricalcium phosphate (β-TCP) blocks are well known biomaterials employed as bone substitutes. Control of the porosity and morphology of these ceramics are important in governing their biological properties upon implantation. One synthetic method, hydrothermal processing, produces porous ceramics with distinct morphologies. In the present study, porous calcium phosphate blocks with unique structures were produced from compacted powder mixtures of alpha-tricalcium phosphate (α-TCP) and glycine (Gly) treated by exposure to water vapor at 120, 160, and 200°C for 5 h. Hydrothermal treatment at 200°C for 5 h of mixtures of Gly/α-TCP with mass ratios of 50/50 and 67/33 could give the porous materials of single phase HA. The obtained porous HA blocks had micrometer-sized pores due to the entanglement of rod-shaped particles, and large-sized pores of over 100μm in diameter derived from Gly. After the heating at 900°C for 3 h in air, HA was converted to β-TCP with almost same microstructure in comparison with that of pre-heating one. The present methods provided insight into the production of porous blocks composed of rod-shaped calcium phosphate particles with both submicron-sized pores and large-sized pores of about 100μm in size.
AB - Porous hydroxyapatite (HA) and beta-tricalcium phosphate (β-TCP) blocks are well known biomaterials employed as bone substitutes. Control of the porosity and morphology of these ceramics are important in governing their biological properties upon implantation. One synthetic method, hydrothermal processing, produces porous ceramics with distinct morphologies. In the present study, porous calcium phosphate blocks with unique structures were produced from compacted powder mixtures of alpha-tricalcium phosphate (α-TCP) and glycine (Gly) treated by exposure to water vapor at 120, 160, and 200°C for 5 h. Hydrothermal treatment at 200°C for 5 h of mixtures of Gly/α-TCP with mass ratios of 50/50 and 67/33 could give the porous materials of single phase HA. The obtained porous HA blocks had micrometer-sized pores due to the entanglement of rod-shaped particles, and large-sized pores of over 100μm in diameter derived from Gly. After the heating at 900°C for 3 h in air, HA was converted to β-TCP with almost same microstructure in comparison with that of pre-heating one. The present methods provided insight into the production of porous blocks composed of rod-shaped calcium phosphate particles with both submicron-sized pores and large-sized pores of about 100μm in size.
KW - Calcium phosphate
KW - Hydrothermal
KW - Hydroxyapatite
KW - Replica
KW - Rod-shaped crystal
KW - β-TCP
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U2 - 10.2109/jcersj2.118.559
DO - 10.2109/jcersj2.118.559
M3 - Article
AN - SCOPUS:77954335072
VL - 118
SP - 559
EP - 563
JO - Nippon Seramikkusu Kyokai Gakujutsu Ronbunshi/Journal of the Ceramic Society of Japan
JF - Nippon Seramikkusu Kyokai Gakujutsu Ronbunshi/Journal of the Ceramic Society of Japan
SN - 1882-0743
IS - 1379
ER -