Fabrication of novel biocompatible surfaces by two-photon absorption technique using femtosecond laser

Masaru Tanaka, Hirokazu Sato, Yugo Sasaya, Suguru Horinouchi, Jun Ichi Hotta, Yasutaka Matsuo, Kuniharu Ijiro, Keiji Sasaki, Masatsugu Shimomura

    Research output: Contribution to journalArticle

    2 Citations (Scopus)

    Abstract

    This study describes the preparation of biocompatible patterned surfaces by a two-photon absorption technique. We have synthesized poly(2-methoxyethyl acrylate) copolymers, which exhibit biocompatibility and photocrosslinking moiety. Fabrication resolution can be controlled in the sub-micrometer range by changing the laser power, photoinitiator concentration, and scanning speed. The patterned surfaces showed excellent human platelet compatibility. Biocompatible patterned surfaces can be used in various medical devices, implants, biosensor chips, and tissue engineering scaffolds.

    Original languageEnglish
    Pages (from-to)219/[457]-230/[468]
    JournalMolecular crystals and liquid crystals
    Volume505
    Issue number1
    DOIs
    Publication statusPublished - 2009

    Keywords

    • Bibi Biocompatible polymer
    • Fabrication
    • Platelet adhesion
    • Poly(2-methoxyethyl acrylate)
    • Scaffold
    • Two-photon

    ASJC Scopus subject areas

    • Chemistry(all)
    • Materials Science(all)
    • Condensed Matter Physics

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  • Cite this

    Tanaka, M., Sato, H., Sasaya, Y., Horinouchi, S., Hotta, J. I., Matsuo, Y., Ijiro, K., Sasaki, K., & Shimomura, M. (2009). Fabrication of novel biocompatible surfaces by two-photon absorption technique using femtosecond laser. Molecular crystals and liquid crystals, 505(1), 219/[457]-230/[468]. https://doi.org/10.1080/15421400902950121