Fabrication of FePt/SiO2 composite magnetic beads

Teruaki Fuchigami, Ryo Kawamura, Yohtaro Yamazaki, Yoshitaka Kitamoto, Masaru Nakagawa, Yoshihisa Namiki

    Research output: Contribution to journalArticlepeer-review

    1 Citation (Scopus)


    The present paper describes effects of organic molecules such as polymers and low molecular surfactants for chemical synthesis of magnetic core-shell FFePt/SiO2 composite microspheres for biomedical applications such as the magnetic hyperthermia and the magnetically guided drug delivery system in cancer therapy. We obtained FePt/SiO2 composite microspheres approximately 330 nm in diameter with a thin shell of 5 nm in thickness by synthesizing FePt nanoparticles on silica microspheres modified with polydiallyldimethylammonium chloride (PDDA). The magnetic shell of 5 nm in thickness is a nanohybrid composed of FePt nanoparticles of approximately 3-4 nm in size and a single-layer of the polymer. The FePt/PDDA/SiO2 core-shell particles exhibit ferromagnetic features at room temperature because the Fe-Pt nanoparticles with ordered-alloy phase are formed with the aid of PDDA despite of small size. The blocking temperature depends on the synthesis temperature of FePt nanoparticles.

    Original languageEnglish
    Pages (from-to)636-641
    Number of pages6
    JournalFuntai Oyobi Fummatsu Yakin/Journal of the Japan Society of Powder and Powder Metallurgy
    Issue number9
    Publication statusPublished - 2010 Sep


    • Biomedical applications
    • Core-shell structure
    • FePt nanoparticles
    • Polymer
    • Polyol method

    ASJC Scopus subject areas

    • Mechanical Engineering
    • Industrial and Manufacturing Engineering
    • Metals and Alloys
    • Materials Chemistry


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