Fabrication of FePt/SiO2 composite magnetic beads

Teruaki Fuchigami, Ryo Kawamura, Yohtaro Yamazaki, Yoshitaka Kitamoto, Masaru Nakagawa, Yoshihisa Namiki

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


The present paper describes effects of organic molecules such as polymers and low molecular surfactants for chemical synthesis of magnetic core-shell FFePt/SiO2 composite microspheres for biomedical applications such as the magnetic hyperthermia and the magnetically guided drug delivery system in cancer therapy. We obtained FePt/SiO2 composite microspheres approximately 330 nm in diameter with a thin shell of 5 nm in thickness by synthesizing FePt nanoparticles on silica microspheres modified with polydiallyldimethylammonium chloride (PDDA). The magnetic shell of 5 nm in thickness is a nanohybrid composed of FePt nanoparticles of approximately 3-4 nm in size and a single-layer of the polymer. The FePt/PDDA/SiO2 core-shell particles exhibit ferromagnetic features at room temperature because the Fe-Pt nanoparticles with ordered-alloy phase are formed with the aid of PDDA despite of small size. The blocking temperature depends on the synthesis temperature of FePt nanoparticles.

Original languageEnglish
Pages (from-to)636-641
Number of pages6
JournalFuntai Oyobi Fummatsu Yakin/Journal of the Japan Society of Powder and Powder Metallurgy
Issue number9
Publication statusPublished - 2010 Sep


  • Biomedical applications
  • Core-shell structure
  • FePt nanoparticles
  • Polymer
  • Polyol method

ASJC Scopus subject areas

  • Mechanical Engineering
  • Industrial and Manufacturing Engineering
  • Metals and Alloys
  • Materials Chemistry

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