Abstract
The present paper describes effects of organic molecules such as polymers and low molecular surfactants for chemical synthesis of magnetic core-shell FFePt/SiO2 composite microspheres for biomedical applications such as the magnetic hyperthermia and the magnetically guided drug delivery system in cancer therapy. We obtained FePt/SiO2 composite microspheres approximately 330 nm in diameter with a thin shell of 5 nm in thickness by synthesizing FePt nanoparticles on silica microspheres modified with polydiallyldimethylammonium chloride (PDDA). The magnetic shell of 5 nm in thickness is a nanohybrid composed of FePt nanoparticles of approximately 3-4 nm in size and a single-layer of the polymer. The FePt/PDDA/SiO2 core-shell particles exhibit ferromagnetic features at room temperature because the Fe-Pt nanoparticles with ordered-alloy phase are formed with the aid of PDDA despite of small size. The blocking temperature depends on the synthesis temperature of FePt nanoparticles.
Original language | English |
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Pages (from-to) | 636-641 |
Number of pages | 6 |
Journal | Funtai Oyobi Fummatsu Yakin/Journal of the Japan Society of Powder and Powder Metallurgy |
Volume | 57 |
Issue number | 9 |
DOIs | |
Publication status | Published - 2010 Sep |
Keywords
- Biomedical applications
- Core-shell structure
- FePt nanoparticles
- Polymer
- Polyol method
ASJC Scopus subject areas
- Mechanical Engineering
- Industrial and Manufacturing Engineering
- Metals and Alloys
- Materials Chemistry