Fabrication of bioceramic scaffolds with ordered pore structure by inverse replication of assembled particles

Kenta Takagi, Takefumi Takahashi, Keiko Kikuchi, Akira Kawasaki

Research output: Contribution to journalArticlepeer-review

16 Citations (Scopus)

Abstract

Β-Tricalcium phosphate (β-TCP) scaffolds with an ordered pore structure were fabricated by ceramic slip casting using a particle-assembled template. An ordered pore structure is expected to enable uniform and accurate improvement in the topology of the porous structure of scaffolds. Monosized spherical polyethylene particles were self-assembled into an fcc lattice by close-packing with a pyramidal indentation and heat-treated for interparticle necking β-TCP slurry was cast with this particle array, followed by heat treatments to burn out the particles and sinter the β-TCP frame. The sintered scaffold showed not only an ordered arrangement of uniform pores but also pore interconnection pathways, which faithfully replicated the particle-assembled structure. High porosity, high pore interconnectivity, and structural controllability, as well as high accessibility, were achieved by this process.

Original languageEnglish
Pages (from-to)2049-2055
Number of pages7
JournalJournal of the European Ceramic Society
Volume30
Issue number10
DOIs
Publication statusPublished - 2010 Aug 1

Keywords

  • Biomedical applications
  • Particle self-assembly
  • Porosity
  • Slip casting

ASJC Scopus subject areas

  • Ceramics and Composites
  • Materials Chemistry

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