Extranodal marginal zone B-cell lymphoma of Mucosa-associated lymphoid tissue (MALT Lymphoma) in the thymus: Report of four cases

Kimihiro Shimizu; Genichiro Ishii; Kanji Nagai; Tomoyuki Yokose; Kenichi Ishizawa; Junichi Tamaru; Junji Yoshida; Mituyo Nishimura; Atushi Ochiai

doi:10.1093/jjco/hyi105

Extranodal marginal zone B-cell lymphoma of Mucosa-associated lymphoid tissue (MALT Lymphoma) in the thymus: Report of four cases

Kimihiro Shimizu, Genichiro Ishii, Kanji Nagai, Tomoyuki Yokose, Kenichi Ishizawa, Junichi Tamaru, Junji Yoshida, Mituyo Nishimura, Atushi Ochiai

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34 Citations (Scopus)

Abstract

Mucosa-associated lymphoid tissue (MALT) lymphoma in the thymus is extremely rare, and little is known about its clinicopathological features. In this study, we examined four cases of MALT lymphoma in the thymus at our institute in terms of clinicopathological features. Most patients had autoimmune disease or hyperglobulinemia, and they also had cysts in the tumors. Both elevated serum levels of autoantibodies and the polyclonal increase in serum Ig remained almost unchanged after total thymectomy in all patients. We recommend that MALT lymphoma in the thymus should be considered in the differential diagnosis when a cystic thymic mass is found and if the patient is Asian and/or has autoimmune disease or hyperglobulinemia.

Original language	English
Pages (from-to)	412-416
Number of pages	5
Journal	Japanese journal of clinical oncology
Volume	35
Issue number	7
DOIs	https://doi.org/10.1093/jjco/hyi105
Publication status	Published - 2005 Jul

Keywords

Aautoimmune disease
Hyperglobulinemia
MALT lymphoma
Thymus

ASJC Scopus subject areas

Oncology
Radiology Nuclear Medicine and imaging
Cancer Research

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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title = "Extranodal marginal zone B-cell lymphoma of Mucosa-associated lymphoid tissue (MALT Lymphoma) in the thymus: Report of four cases",

abstract = "Mucosa-associated lymphoid tissue (MALT) lymphoma in the thymus is extremely rare, and little is known about its clinicopathological features. In this study, we examined four cases of MALT lymphoma in the thymus at our institute in terms of clinicopathological features. Most patients had autoimmune disease or hyperglobulinemia, and they also had cysts in the tumors. Both elevated serum levels of autoantibodies and the polyclonal increase in serum Ig remained almost unchanged after total thymectomy in all patients. We recommend that MALT lymphoma in the thymus should be considered in the differential diagnosis when a cystic thymic mass is found and if the patient is Asian and/or has autoimmune disease or hyperglobulinemia.",

keywords = "Aautoimmune disease, Hyperglobulinemia, MALT lymphoma, Thymus",

author = "Kimihiro Shimizu and Genichiro Ishii and Kanji Nagai and Tomoyuki Yokose and Kenichi Ishizawa and Junichi Tamaru and Junji Yoshida and Mituyo Nishimura and Atushi Ochiai",

note = "Funding Information: This work was supported in part by a Grant-in-Aid for cancer research from the Ministry of Health, Labour and Welfare, Japan.",

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language = "English",

volume = "35",

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T1 - Extranodal marginal zone B-cell lymphoma of Mucosa-associated lymphoid tissue (MALT Lymphoma) in the thymus

T2 - Report of four cases

AU - Shimizu, Kimihiro

AU - Ishii, Genichiro

AU - Nagai, Kanji

AU - Yokose, Tomoyuki

AU - Ishizawa, Kenichi

AU - Tamaru, Junichi

AU - Yoshida, Junji

AU - Nishimura, Mituyo

AU - Ochiai, Atushi

N1 - Funding Information: This work was supported in part by a Grant-in-Aid for cancer research from the Ministry of Health, Labour and Welfare, Japan.

PY - 2005/7

Y1 - 2005/7

N2 - Mucosa-associated lymphoid tissue (MALT) lymphoma in the thymus is extremely rare, and little is known about its clinicopathological features. In this study, we examined four cases of MALT lymphoma in the thymus at our institute in terms of clinicopathological features. Most patients had autoimmune disease or hyperglobulinemia, and they also had cysts in the tumors. Both elevated serum levels of autoantibodies and the polyclonal increase in serum Ig remained almost unchanged after total thymectomy in all patients. We recommend that MALT lymphoma in the thymus should be considered in the differential diagnosis when a cystic thymic mass is found and if the patient is Asian and/or has autoimmune disease or hyperglobulinemia.

AB - Mucosa-associated lymphoid tissue (MALT) lymphoma in the thymus is extremely rare, and little is known about its clinicopathological features. In this study, we examined four cases of MALT lymphoma in the thymus at our institute in terms of clinicopathological features. Most patients had autoimmune disease or hyperglobulinemia, and they also had cysts in the tumors. Both elevated serum levels of autoantibodies and the polyclonal increase in serum Ig remained almost unchanged after total thymectomy in all patients. We recommend that MALT lymphoma in the thymus should be considered in the differential diagnosis when a cystic thymic mass is found and if the patient is Asian and/or has autoimmune disease or hyperglobulinemia.

KW - Aautoimmune disease

KW - Hyperglobulinemia

KW - MALT lymphoma

KW - Thymus

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ER -

Extranodal marginal zone B-cell lymphoma of Mucosa-associated lymphoid tissue (MALT Lymphoma) in the thymus: Report of four cases

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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