Extranodal marginal zone B-cell lymphoma of Mucosa-associated lymphoid tissue (MALT Lymphoma) in the thymus: Report of four cases

Kimihiro Shimizu, Genichiro Ishii, Kanji Nagai, Tomoyuki Yokose, Kenichi Ishizawa, Junichi Tamaru, Junji Yoshida, Mituyo Nishimura, Atushi Ochiai

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Mucosa-associated lymphoid tissue (MALT) lymphoma in the thymus is extremely rare, and little is known about its clinicopathological features. In this study, we examined four cases of MALT lymphoma in the thymus at our institute in terms of clinicopathological features. Most patients had autoimmune disease or hyperglobulinemia, and they also had cysts in the tumors. Both elevated serum levels of autoantibodies and the polyclonal increase in serum Ig remained almost unchanged after total thymectomy in all patients. We recommend that MALT lymphoma in the thymus should be considered in the differential diagnosis when a cystic thymic mass is found and if the patient is Asian and/or has autoimmune disease or hyperglobulinemia.

Original languageEnglish
Pages (from-to)412-416
Number of pages5
JournalJapanese journal of clinical oncology
Volume35
Issue number7
DOIs
Publication statusPublished - 2005 Jul
Externally publishedYes

Keywords

  • Aautoimmune disease
  • Hyperglobulinemia
  • MALT lymphoma
  • Thymus

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Cancer Research

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