Extradural granulocytic sarcoma of the thoracic spine in acute myelogenous leukemia with 8 ; 21 chromosome translocation

Toshimi Aizawa; Shoichi Kokubun; Masahito Hatori; Osamu Kashimoto; Ryo Ichinohasama

doi:10.1620/tjem.178.431

Extradural granulocytic sarcoma of the thoracic spine in acute myelogenous leukemia with 8 ; 21 chromosome translocation

Toshimi Aizawa, Shoichi Kokubun, Masahito Hatori, Osamu Kashimoto, Ryo Ichinohasama

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

We report a case of a 19-year-old male with an extradural granulocytic sarcoma at T5/6 to T7 demonstrated by MRI. He recovered from paraplegia that had progressed rapidly after excision of the tumor as an emergency operation. Histopathological studies disclosed granulocytic sarcoma. Both peripheral blood and bone marrow examinations revealed acute myelogenous leukemia. The karyotype of the bone marrow showed 45, X, -Y, t (8 ; 21) (q22 ; q22).

Original language	English
Pages (from-to)	431-436
Number of pages	6
Journal	Tohoku Journal of Experimental Medicine
Volume	178
Issue number	4
DOIs	https://doi.org/10.1620/tjem.178.431
Publication status	Published - 1996 Apr

Keywords

21 translocation
8
Acute myelogenous leukemia
Chromosome abnormality
Epidural tumor
Granulocytic sarcoma

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

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10.1620/tjem.178.431

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title = "Extradural granulocytic sarcoma of the thoracic spine in acute myelogenous leukemia with 8 ; 21 chromosome translocation",

abstract = "We report a case of a 19-year-old male with an extradural granulocytic sarcoma at T5/6 to T7 demonstrated by MRI. He recovered from paraplegia that had progressed rapidly after excision of the tumor as an emergency operation. Histopathological studies disclosed granulocytic sarcoma. Both peripheral blood and bone marrow examinations revealed acute myelogenous leukemia. The karyotype of the bone marrow showed 45, X, -Y, t (8 ; 21) (q22 ; q22).",

keywords = "21 translocation, 8, Acute myelogenous leukemia, Chromosome abnormality, Epidural tumor, Granulocytic sarcoma",

author = "Toshimi Aizawa and Shoichi Kokubun and Masahito Hatori and Osamu Kashimoto and Ryo Ichinohasama",

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T1 - Extradural granulocytic sarcoma of the thoracic spine in acute myelogenous leukemia with 8 ; 21 chromosome translocation

AU - Aizawa, Toshimi

AU - Kokubun, Shoichi

AU - Hatori, Masahito

AU - Kashimoto, Osamu

AU - Ichinohasama, Ryo

PY - 1996/4

Y1 - 1996/4

N2 - We report a case of a 19-year-old male with an extradural granulocytic sarcoma at T5/6 to T7 demonstrated by MRI. He recovered from paraplegia that had progressed rapidly after excision of the tumor as an emergency operation. Histopathological studies disclosed granulocytic sarcoma. Both peripheral blood and bone marrow examinations revealed acute myelogenous leukemia. The karyotype of the bone marrow showed 45, X, -Y, t (8 ; 21) (q22 ; q22).

AB - We report a case of a 19-year-old male with an extradural granulocytic sarcoma at T5/6 to T7 demonstrated by MRI. He recovered from paraplegia that had progressed rapidly after excision of the tumor as an emergency operation. Histopathological studies disclosed granulocytic sarcoma. Both peripheral blood and bone marrow examinations revealed acute myelogenous leukemia. The karyotype of the bone marrow showed 45, X, -Y, t (8 ; 21) (q22 ; q22).

KW - 21 translocation

KW - 8

KW - Acute myelogenous leukemia

KW - Chromosome abnormality

KW - Epidural tumor

KW - Granulocytic sarcoma

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Extradural granulocytic sarcoma of the thoracic spine in acute myelogenous leukemia with 8 ; 21 chromosome translocation

Abstract

Keywords

ASJC Scopus subject areas

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