External Reversible Control of Recognition Behavior of Alpha-Peptide Ribonucleic Acid (α-PRNA) Through anti-syn Orientational Switching of the Nucleobase Induced by Borate Esterification of the cis-2′,3′-Diol

Takehiko Wada, Hirofumi Sato, Yoshihisa Inoue

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

A novel nucleic acid model using peptide ribonucleic acid (PRNA), which contains 5′-amino-5′-deoxypyrimidine ribonucleoside as a recognition site for nucleic acids, has been designed, synthesized and applied to the external reversible control of recognition behavior of the complementary polynucleotide through the orientational switching of the nucleobase induced by borate.

Original languageEnglish
Pages (from-to)15-20
Number of pages6
JournalBiopolymers - Peptide Science Section
Volume76
Issue number1
DOIs
Publication statusPublished - 2004 Mar 24
Externally publishedYes

Keywords

  • Anti-syn switching
  • Borate
  • PRNA

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Biomaterials
  • Organic Chemistry

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