Expression patterns of four different regulatory genes that function during sea urchin development

Takuya Minokawa, Jonathan P. Rast, Cesar Arenas-Mena, Christopher B. Franco, Eric H. Davidson

Research output: Contribution to journalArticlepeer-review

115 Citations (Scopus)

Abstract

The spatial and temporal expression patterns of Strongylocentrotus purpuratus genes encoding four different transcription factors, viz. SpFoxb, SpHes, SpKrl, and SpNk1, have been examined, using a recently developed, highly sensitive whole mount in situ hybridization procedure, and quantitative real time PCR. Two of the genes studied, SpHes and SpNk1, are newly isolated. Their expression patterns suggest the existence of previously unknown ectodermal domains. Re-examination of the expression pattern of SpFoxb reveals domains of expression not previously reported for this gene, and we also provide a more detailed, temporal and spatial description of the expression pattern of SpKrl than heretofore available.

Original languageEnglish
Pages (from-to)449-456
Number of pages8
JournalGene Expression Patterns
Volume4
Issue number4
DOIs
Publication statusPublished - 2004 Jul
Externally publishedYes

Keywords

  • Gene regulatory network
  • Homeobox
  • Oral ectoderm
  • Primary mesenchyme cell
  • Sea urchin
  • Transcription factor
  • bHLH
  • forkhead
  • foxb
  • hairy/enhancer of split
  • hes
  • krüppel-like
  • nk1
  • nkx

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics
  • Developmental Biology

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