Expression of rat type 2Cα protein phosphatase in Saccharomyces cerevisiae cells

T. Kobayashi; M. Ohnishi; Shunsuke Kato; Y. Sasahara; S. Tamura

Expression of rat type 2Cα protein phosphatase in Saccharomyces cerevisiae cells

T. Kobayashi, M. Ohnishi, Shunsuke Kato, Y. Sasahara, S. Tamura

Research output: Contribution to journal › Article › peer-review

Abstract

In the course of a study to elucidate the physiological functions of type 2C protein phosphatase(PP2C), we investigated the effects of overexpression of the enzyme protein on the physiology of eukaryotes. In this study, we demonstrated that the overexpression of PP2Cα caused a decreased growth rate and an increased UV-sensitivity of the yeast cells. We also showed that the expressed PP2C was phosphorylated by casein kinase II in the cells.

Original language	English
Pages (from-to)	325-329
Number of pages	5
Journal	Japanese Journal of Cancer and Chemotherapy
Volume	21
Issue number	3
Publication status	Published - 1994 Jan 1
Externally published	Yes

ASJC Scopus subject areas

Oncology
Cancer Research

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title = "Expression of rat type 2Cα protein phosphatase in Saccharomyces cerevisiae cells",

abstract = "In the course of a study to elucidate the physiological functions of type 2C protein phosphatase(PP2C), we investigated the effects of overexpression of the enzyme protein on the physiology of eukaryotes. In this study, we demonstrated that the overexpression of PP2Cα caused a decreased growth rate and an increased UV-sensitivity of the yeast cells. We also showed that the expressed PP2C was phosphorylated by casein kinase II in the cells.",

author = "T. Kobayashi and M. Ohnishi and Shunsuke Kato and Y. Sasahara and S. Tamura",

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AU - Ohnishi, M.

AU - Kato, Shunsuke

AU - Sasahara, Y.

AU - Tamura, S.

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