Expression of connexin 30 in the developing mouse cochlea

An Ping Xia, Yukio Katori, Takeshi Oshima, Kojiro Watanabe, Toshihiko Kikuchi, Katsuhisa Ikeda

Research output: Contribution to journalArticlepeer-review

30 Citations (Scopus)

Abstract

Mutations in the GJB6 gene encoding connexin 30 (Cx30) can cause dominant forms of nonsyndromic deafness. By studying immunohistochemical localization of Cx30 in the mouse cochlea at different ages from 0 to 30 days after birth, we found that the expression of Cx30 is nearly the same as that of Cx26. These findings suggest that as well as Cx26, Cx30 may also contribute to the generation and maturation of endocochlear potential.

Original languageEnglish
Pages (from-to)364-367
Number of pages4
JournalBrain research
Volume898
Issue number2
DOIs
Publication statusPublished - 2001 Apr 20

Keywords

  • Connexin 30
  • Development
  • Endocochlear potential
  • Fibrocytes
  • RT-PCR

ASJC Scopus subject areas

  • Neuroscience(all)
  • Molecular Biology
  • Clinical Neurology
  • Developmental Biology

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