Experimental tooth movement upregulates preproenkephalin mRNA in the rat trigeminal nucleus caudalis and oralis

Tarek A. Balam; Takashi Yamashiro; Li Zheng; Sakhr Murshid Ahmed; Yoshiaki Fujiyoshi; Teruko Takano-Yamamoto

doi:10.1016/j.brainres.2004.11.056

Experimental tooth movement upregulates preproenkephalin mRNA in the rat trigeminal nucleus caudalis and oralis

Tarek A. Balam, Takashi Yamashiro, Li Zheng, Sakhr Murshid Ahmed, Yoshiaki Fujiyoshi, Teruko Takano-Yamamoto

Research output: Contribution to journal › Article › peer-review

18 Citations (Scopus)

Abstract

Levels of preproenkephalin mRNA expression in trigeminal subnucleus complex by noxious tooth movement stimuli were examined using in situ hybridization. At 24 h, preproenkephalin mRNA expression was significantly upregulated in the ipsilateral trigeminal subnucleus caudalis (P < 0.05), and in the subnucleus oralis (P < 0.05). These findings suggested that enkephalinergic inhibitory systems could be activated during tooth movement, and that subnucleus oralis may be involved in modulation of the nociception, as well as the subnucleus caudalis.

Original language	English
Pages (from-to)	196-201
Number of pages	6
Journal	Brain research
Volume	1036
Issue number	1-2
DOIs	https://doi.org/10.1016/j.brainres.2004.11.056
Publication status	Published - 2005 Mar 2
Externally published	Yes

Keywords

Pain modulation
Preproenkephalin
Subnucleus caudalis
Subnucleus oralis
Tooth movement

ASJC Scopus subject areas

Neuroscience(all)
Molecular Biology
Clinical Neurology
Developmental Biology

Access to Document

10.1016/j.brainres.2004.11.056

Cite this

@article{d5d91e3f01774ce6962b90de2e138a93,

title = "Experimental tooth movement upregulates preproenkephalin mRNA in the rat trigeminal nucleus caudalis and oralis",

abstract = "Levels of preproenkephalin mRNA expression in trigeminal subnucleus complex by noxious tooth movement stimuli were examined using in situ hybridization. At 24 h, preproenkephalin mRNA expression was significantly upregulated in the ipsilateral trigeminal subnucleus caudalis (P < 0.05), and in the subnucleus oralis (P < 0.05). These findings suggested that enkephalinergic inhibitory systems could be activated during tooth movement, and that subnucleus oralis may be involved in modulation of the nociception, as well as the subnucleus caudalis.",

keywords = "Pain modulation, Preproenkephalin, Subnucleus caudalis, Subnucleus oralis, Tooth movement",

author = "Balam, {Tarek A.} and Takashi Yamashiro and Li Zheng and Ahmed, {Sakhr Murshid} and Yoshiaki Fujiyoshi and Teruko Takano-Yamamoto",

note = "Funding Information: This study was supported by a Grant-In-Aid for Scientific Research from Japan Society for the Promotion of Science (14571948, 14207092, 15390635).",

year = "2005",

month = mar,

day = "2",

doi = "10.1016/j.brainres.2004.11.056",

language = "English",

volume = "1036",

pages = "196--201",

journal = "Molecular Brain Research",

issn = "0006-8993",

publisher = "Elsevier",

number = "1-2",

}

TY - JOUR

T1 - Experimental tooth movement upregulates preproenkephalin mRNA in the rat trigeminal nucleus caudalis and oralis

AU - Balam, Tarek A.

AU - Yamashiro, Takashi

AU - Zheng, Li

AU - Ahmed, Sakhr Murshid

AU - Fujiyoshi, Yoshiaki

AU - Takano-Yamamoto, Teruko

N1 - Funding Information: This study was supported by a Grant-In-Aid for Scientific Research from Japan Society for the Promotion of Science (14571948, 14207092, 15390635).

PY - 2005/3/2

Y1 - 2005/3/2

N2 - Levels of preproenkephalin mRNA expression in trigeminal subnucleus complex by noxious tooth movement stimuli were examined using in situ hybridization. At 24 h, preproenkephalin mRNA expression was significantly upregulated in the ipsilateral trigeminal subnucleus caudalis (P < 0.05), and in the subnucleus oralis (P < 0.05). These findings suggested that enkephalinergic inhibitory systems could be activated during tooth movement, and that subnucleus oralis may be involved in modulation of the nociception, as well as the subnucleus caudalis.

AB - Levels of preproenkephalin mRNA expression in trigeminal subnucleus complex by noxious tooth movement stimuli were examined using in situ hybridization. At 24 h, preproenkephalin mRNA expression was significantly upregulated in the ipsilateral trigeminal subnucleus caudalis (P < 0.05), and in the subnucleus oralis (P < 0.05). These findings suggested that enkephalinergic inhibitory systems could be activated during tooth movement, and that subnucleus oralis may be involved in modulation of the nociception, as well as the subnucleus caudalis.

KW - Pain modulation

KW - Preproenkephalin

KW - Subnucleus caudalis

KW - Subnucleus oralis

KW - Tooth movement

UR - http://www.scopus.com/inward/record.url?scp=13844253807&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=13844253807&partnerID=8YFLogxK

U2 - 10.1016/j.brainres.2004.11.056

DO - 10.1016/j.brainres.2004.11.056

M3 - Article

C2 - 15725418

AN - SCOPUS:13844253807

SN - 0006-8993

VL - 1036

SP - 196

EP - 201

JO - Molecular Brain Research

JF - Molecular Brain Research

IS - 1-2

ER -

Experimental tooth movement upregulates preproenkephalin mRNA in the rat trigeminal nucleus caudalis and oralis

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this