TY - GEN
T1 - Experimental study on flow control of λDNA in electrode-embedded microchannel
AU - Uehara, Satoshi
AU - Yukimoto, Naoya
AU - Shintaku, Hirofumi
AU - Kawano, Satoyuki
PY - 2011/12/1
Y1 - 2011/12/1
N2 - In this paper, we report the experimental study on novel DNA separation using electrode-embedded microchannel. A microchannel with an interdigitated electrode on the wall was developed for investigation. The experiment was carried out with flowing solution including λDNA by pressure driven flow. DC voltage of ∼2 V was applied to the interdigitated electrode. Under the ideal condition, λDNA is trapped on electrode and released from it stochastically. From the observation, it was found that the velocity of λDNA was decreased by the electric field when it approached to a positive electrode. Furthermore, we theoretically estimated the trajectory of flowing λDNA in the microchannel. Comparing the experimental and theoretical results, it was found that the electric field by the interdigitated electrodes was shielded by electrolyte in the solution.
AB - In this paper, we report the experimental study on novel DNA separation using electrode-embedded microchannel. A microchannel with an interdigitated electrode on the wall was developed for investigation. The experiment was carried out with flowing solution including λDNA by pressure driven flow. DC voltage of ∼2 V was applied to the interdigitated electrode. Under the ideal condition, λDNA is trapped on electrode and released from it stochastically. From the observation, it was found that the velocity of λDNA was decreased by the electric field when it approached to a positive electrode. Furthermore, we theoretically estimated the trajectory of flowing λDNA in the microchannel. Comparing the experimental and theoretical results, it was found that the electric field by the interdigitated electrodes was shielded by electrolyte in the solution.
UR - http://www.scopus.com/inward/record.url?scp=84881401729&partnerID=8YFLogxK
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U2 - 10.1115/AJK2011-36039
DO - 10.1115/AJK2011-36039
M3 - Conference contribution
AN - SCOPUS:84881401729
SN - 9780791844410
T3 - ASME-JSME-KSME 2011 Joint Fluids Engineering Conference, AJK 2011
SP - 421
EP - 422
BT - ASME-JSME-KSME 2011 Joint Fluids Engineering Conference, AJK 2011
T2 - ASME-JSME-KSME 2011 Joint Fluids Engineering Conference, AJK 2011
Y2 - 24 July 2011 through 29 July 2011
ER -