Experimental study on flow control of λDNA in electrode-embedded microchannel

Satoshi Uehara, Naoya Yukimoto, Hirofumi Shintaku, Satoyuki Kawano

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In this paper, we report the experimental study on novel DNA separation using electrode-embedded microchannel. A microchannel with an interdigitated electrode on the wall was developed for investigation. The experiment was carried out with flowing solution including λDNA by pressure driven flow. DC voltage of ∼2 V was applied to the interdigitated electrode. Under the ideal condition, λDNA is trapped on electrode and released from it stochastically. From the observation, it was found that the velocity of λDNA was decreased by the electric field when it approached to a positive electrode. Furthermore, we theoretically estimated the trajectory of flowing λDNA in the microchannel. Comparing the experimental and theoretical results, it was found that the electric field by the interdigitated electrodes was shielded by electrolyte in the solution.

Original languageEnglish
Title of host publicationASME-JSME-KSME 2011 Joint Fluids Engineering Conference, AJK 2011
Pages421-422
Number of pages2
DOIs
Publication statusPublished - 2011 Dec 1
Externally publishedYes
EventASME-JSME-KSME 2011 Joint Fluids Engineering Conference, AJK 2011 - Hamamatsu, Japan
Duration: 2011 Jul 242011 Jul 29

Publication series

NameASME-JSME-KSME 2011 Joint Fluids Engineering Conference, AJK 2011
Volume2

Other

OtherASME-JSME-KSME 2011 Joint Fluids Engineering Conference, AJK 2011
CountryJapan
CityHamamatsu
Period11/7/2411/7/29

ASJC Scopus subject areas

  • Fluid Flow and Transfer Processes

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  • Cite this

    Uehara, S., Yukimoto, N., Shintaku, H., & Kawano, S. (2011). Experimental study on flow control of λDNA in electrode-embedded microchannel. In ASME-JSME-KSME 2011 Joint Fluids Engineering Conference, AJK 2011 (pp. 421-422). (ASME-JSME-KSME 2011 Joint Fluids Engineering Conference, AJK 2011; Vol. 2). https://doi.org/10.1115/AJK2011-36039