Experimental study for cancer diagnosis with 18FDG: Differential diagnosis of inflammation from malignant tumor

H. Fukuda, S. Yoshioka, S. Watanuki, M. Kiyosawa, T. Sato, T. Matsuzawa, T. Takahashi, T. Ido

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)


The validity of tumor diagnosis with 18FDG was tested in an experimental rabbit tumor. A male rabbit with a VX2 tumor in the right thigh and croton oil-induced inflammation in the left thigh, was injected with 3 mCi of 18FDG. Just after injection, serial scanning every 3 min was done by positron emission tomography. The total number of images was 20 and each image had no less than 500 k counts. The tumor uptake of 18FDG was high and increased with time during the 60-min study period. Inflammation uptake was lower than that of tumor and relatively constant during the period. This was the important finding that distinguishes inflammation from a malignant tumor and it would be useful information for clinical cancer diagnosis with 18FDG.

Original languageEnglish
Pages (from-to)1189-1192
Number of pages4
Issue number8
Publication statusPublished - 1983 Dec 1
Externally publishedYes

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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