Experimental and theoretical study of anion-exchange preparative chromatography for neptunium: The first application to thorium(IV) and its equilibrium and kinetics

Tomoo Yamamura, Takeshi Miyakoshi, Yoshinobu Shiokawa, Toshiaki Mitsugashira

Research output: Contribution to journalArticlepeer-review

Abstract

In order to study equilibrium and kinetic parameters in anion-exchange chromatography for preparatory purpose, a quantitative model for nonlinear anion-exchange chromatography in porous media was constructed, by paying special attention to interstitial length along void structure (cm) distinguished from apparent length (cm*). Langmuir-type adsorption isotherm for thorium(IV), as a natural substitution for neptunium(IV), in 6 mol dm-3 nitric acid to anion-exchanger MSA-1 (200-400 mesh) was investigated in batch-wise and chromatographic experiments. The equilibrium parameters determined by batch-wise experiments determined as k = 2.4 × 102 mol-1 dm3 s-1 and s0 = 0.5 mol dm-3 agrees very well with the values of k = 222 mol-1 dm3 s-1 and s0 = 0.5 mol dm-3 derived from fitting by the numerical calculation. Kinetic parameters of ks and D affect band profile similarly, thereby maximum value of each parameter was evaluated as ks = 1.3 mol-1 dm3 s-1 and D = 9 × 10-4 cm2 s-1 by the numerical calculations.

Original languageEnglish
Pages (from-to)95-102
Number of pages8
JournalJournal of Chromatography A
Volume1169
Issue number1-2
DOIs
Publication statusPublished - 2007 Oct 26

Keywords

  • Adsorption isotherm
  • Anion-exchange chromatography
  • High-loading condition
  • Kinetics
  • Thorium

ASJC Scopus subject areas

  • Analytical Chemistry
  • Biochemistry
  • Organic Chemistry

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