TY - JOUR
T1 - Experimental and theoretical study of anion-exchange preparative chromatography for neptunium
T2 - The first application to thorium(IV) and its equilibrium and kinetics
AU - Yamamura, Tomoo
AU - Miyakoshi, Takeshi
AU - Shiokawa, Yoshinobu
AU - Mitsugashira, Toshiaki
PY - 2007/10/26
Y1 - 2007/10/26
N2 - In order to study equilibrium and kinetic parameters in anion-exchange chromatography for preparatory purpose, a quantitative model for nonlinear anion-exchange chromatography in porous media was constructed, by paying special attention to interstitial length along void structure (cm) distinguished from apparent length (cm*). Langmuir-type adsorption isotherm for thorium(IV), as a natural substitution for neptunium(IV), in 6 mol dm-3 nitric acid to anion-exchanger MSA-1 (200-400 mesh) was investigated in batch-wise and chromatographic experiments. The equilibrium parameters determined by batch-wise experiments determined as k = 2.4 × 102 mol-1 dm3 s-1 and s0 = 0.5 mol dm-3 agrees very well with the values of k = 222 mol-1 dm3 s-1 and s0 = 0.5 mol dm-3 derived from fitting by the numerical calculation. Kinetic parameters of ks and D affect band profile similarly, thereby maximum value of each parameter was evaluated as ks = 1.3 mol-1 dm3 s-1 and D = 9 × 10-4 cm2 s-1 by the numerical calculations.
AB - In order to study equilibrium and kinetic parameters in anion-exchange chromatography for preparatory purpose, a quantitative model for nonlinear anion-exchange chromatography in porous media was constructed, by paying special attention to interstitial length along void structure (cm) distinguished from apparent length (cm*). Langmuir-type adsorption isotherm for thorium(IV), as a natural substitution for neptunium(IV), in 6 mol dm-3 nitric acid to anion-exchanger MSA-1 (200-400 mesh) was investigated in batch-wise and chromatographic experiments. The equilibrium parameters determined by batch-wise experiments determined as k = 2.4 × 102 mol-1 dm3 s-1 and s0 = 0.5 mol dm-3 agrees very well with the values of k = 222 mol-1 dm3 s-1 and s0 = 0.5 mol dm-3 derived from fitting by the numerical calculation. Kinetic parameters of ks and D affect band profile similarly, thereby maximum value of each parameter was evaluated as ks = 1.3 mol-1 dm3 s-1 and D = 9 × 10-4 cm2 s-1 by the numerical calculations.
KW - Adsorption isotherm
KW - Anion-exchange chromatography
KW - High-loading condition
KW - Kinetics
KW - Thorium
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U2 - 10.1016/j.chroma.2007.08.076
DO - 10.1016/j.chroma.2007.08.076
M3 - Article
C2 - 17880985
AN - SCOPUS:34848876939
VL - 1169
SP - 95
EP - 102
JO - Journal of Chromatography
JF - Journal of Chromatography
SN - 0021-9673
IS - 1-2
ER -