Experience with artificial liver support in 16 living related liver transplant recipients

Naoki Kawagishi, Nobuhiro Ohkohchi, Keisei Fujimori, Takashi Orii, Nozomi Koyamada, Hiroyuki Kikuchi, Susumu Satomi

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)

Abstract

This study was a retrospective investigation about the indication and efficacy of artifical liver support for liver transplant recipients. Apheresis was performed in 16 of 41 patients subjected to living related liver transplantation (LRLTx) as articial liver support, including plasmapheresis (PP) in 13 cases, continuous hemodiafiltration (CHDF) in 7 cases, and plasma adsorption (PA) in 2 cases. One patient with cryptogenic liver cirrhosis was subjected to PP before the LRLTx, and the result was satisfactory. On the contrary, the results of PP and CHDF for graft, respiratory, or cardiac failure were not acceptable. Only 1 patient survived despite multiple organ failure. Both PP and PA for patients with hyperbilirubinemia were effective and improved their critical conditions. We conclude that apheresis for liver transplant patients is effective to treat hyperbilirubinemia, but it is not indicated for respiratory and cardiac failure nor for hepatic failure.

Original languageEnglish
Pages (from-to)7-11
Number of pages5
JournalTherapeutic Apheresis
Volume5
Issue number1
DOIs
Publication statusPublished - 2001

Keywords

  • Artificial liver support
  • Liver transplantation
  • Living donor

ASJC Scopus subject areas

  • Medicine(all)

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