Abstract
The Au-catalyzed reactions of O-homopropaylic oximes afforded the 3-alkenylated isoxazolines in good to high yields. The mechanistic studies suggest that the reaction proceeds through an exo-cyclization followed by intermolecular methylene group transfer. In addition, oligomeric species of the starting material were observed in the reaction mixture by mass spectra, supporting our proposed mechanism, which proceeds through a repeated intermolecular C−C bond forming process.
Original language | English |
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Pages (from-to) | 15816-15820 |
Number of pages | 5 |
Journal | Chemistry - A European Journal |
Volume | 26 |
Issue number | 68 |
DOIs | |
Publication status | Published - 2020 Dec 4 |
Keywords
- alkynes
- cascade reactions
- gold catalysts
- heterocycles
- rearrangement
ASJC Scopus subject areas
- Catalysis
- Organic Chemistry