Evidence of indications of influenza vaccine and its efficacy--including Guillain-Barré syndrome as an adverse reaction(?)

Akira Watanabe

    Research output: Contribution to journalReview articlepeer-review

    Abstract

    With respect to the indications of influenza vaccine, the US CDC guidelines are the most rational. All people aged not less than 50 years old, patients with pulmonary diseases, cardiac diseases and metabolic diseases such as diabetes mellitus, residents in old-age homes, high-risk subjects such as pregnant women, medical professionals at the position liable to infect the populations with influenza, employees of institutions, persons in charge of home care, and lodgers with high-risk patients are the subjects recommended for vaccination. There are many evidences of the efficacy of influenza vaccine in the world, and recently, it has been reported that vaccination has significantly reduced hospitalization and death due to not only influenza and pneumonia but also other diseases such as cerebrovascular diseases and cardiac diseases. Since Guillain-Barré syndrome which has been considered an adverse reaction of influenza vaccine was attributable to the swine influenza vaccine (swine type virus vaccine) used in the USA in the season from 1976 to 1977 and no incidence in the syndrome has been reported with subsequent vaccines, this syndrome does not become a reason for avoidance from vaccination in the subjects other than those with a history of the syndrome.

    Original languageEnglish
    Pages (from-to)1987-1991
    Number of pages5
    JournalNippon rinsho. Japanese journal of clinical medicine
    Volume61
    Issue number11
    Publication statusPublished - 2003 Nov

    ASJC Scopus subject areas

    • Medicine(all)

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