Evidence for an enolate mechanism in the asymmetric Michael reaction of α,β-unsaturated aldehydes and ketones: Via a hybrid system of two secondary amine catalysts

Chemistry

• Enolates 100%
• Catalyst 75%
• Ketone 50%
• Nucleophile 50%
• Aldehyde 50%
• Ketones 50%
• Secondary Amine 50%
• Asymmetry 50%
• Enamine 50%
• Chemical Reaction 50%
• Michael Reaction 50%
• Amine 25%
• Silyl Ether 25%
• Enol 25%
• Base 25%
• Reaction Mechanism 25%
• Organocatalysis 25%
• Pyrrolidine 25%