Evaluation of total peripheral resistance in using a left ventricular assist device

H. Akiho, S. Nitta, Tomoyuki Yambe, S. Naganuma, Y. Kakinuma, K. Izutsu, S. Kobayashi, S. Nanka, M. Tanaka, T. Fukuju, M. Miura, N. Sato, H. Mohri, S. Koide, K. Abe, H. Takeda, T. Kasai, H. Hashimoto, Makoto Yoshizawa

Research output: Contribution to journalArticlepeer-review


To determine optimal driving modes of left ventricular assist device (LVAD) for the natural heart, acute experiments were performed in 8 adult goats. LVAD bypass flow was maintained within same value during the use of co-pulsation mode and conterpulsation mode by our adaptive control system. Total peripheral vascular resistance and natural heart output during each driving mode were evaluated. Total peripheral resistances were not significantly changed during each driving mode though natural heart output increased during the use of counterpulsation mode compared with co-pulsation mode. These results suggested that afterload of the natural heart was decreased during the use of counterpulsation mode and counterpulsation mode was desirable for the natural heart unloading.

Original languageEnglish
Pages (from-to)71-75
Number of pages5
JournalJapanese Journal of Artificial Organs
Issue number1
Publication statusPublished - 1994 Jan 1

ASJC Scopus subject areas

  • Biophysics


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