Evaluation of Rupture Properties of Thoracic Aortic Aneurysms in a Pressure-Imposed Test for Rupture Risk Estimation

Shukei Sugita, Takeo Matsumoto, Toshiro Ohashi, Kiichiro Kumagai, Hiroji Akimoto, Koichi Tabayashi, Masaaki Sato

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

Rupture properties of thoracic aortic aneurysms (TAAs) were measured in vitro in a pressure-imposed test to predict the ultimate stress of TAAs from their mechanical behavior in a physiological pressure range. Each quadrilateral (ca. 20 × 20 mm2) specimen of TAAs or porcine thoracic aortas (PTAs) was pressurized from the inner wall until rupture or up to 4500 mmHg, while its deformation was being monitored. In-plane stress σ and strain ε of the specimen were calculated using Laplace's law and deformations of the markers drawn on the specimen surface, respectively. Ultimate stress σmax and tangent elastic modulus H were determined from the σ-ε curve as its maximum stress and slope, respectively. The tangent elastic modulus H of PTA specimens tended to increase with the increase in σ, while that of TAA specimens tended to reach a plateau in a low-σ region. This tendency was confirmed by fitting a function H = Cσ(1 - exp(-σ/τσ)) to the H-σ relation of specimens: The yielding parameter τσ was significantly lower in TAAs than PTAs. Furthermore, the logarithm of the parameter τσ correlated significantly with σmax, for all specimens. These results may indicate that τσ is one of the candidate indices for rupture risk estimation.

Original languageEnglish
Pages (from-to)41-51
Number of pages11
JournalCardiovascular Engineering and Technology
Volume3
Issue number1
DOIs
Publication statusPublished - 2012 Mar 1

Keywords

  • Mechanical property
  • Pressure-imposed test
  • Rupture estimation
  • Tangent elastic modulus
  • Thoracic aortic aneurysm

ASJC Scopus subject areas

  • Biomedical Engineering
  • Cardiology and Cardiovascular Medicine

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