A preliminary study was performed to determine whether ultrafast computed tomography (UFCT) is useful as a noninvasive screening examination for predicting coronary artery disease (CAD). UFCT was used to detect coronary artery calcification in 31 patients with angina pectoris (AP) without myocardial infarction. Except for six patients with vasospastic AP, 22 out of 25 patients had detectable calcification in at least one vessel. SVD, DVD and TVD were detected in six of nine patients (67%), seven of seven (100%) and nine of nine (100%), respectively. Based on the findings of coronary calcification by UFCT, the sensitivity, specificity and predictive accuracy of angiographically significant stenosis (greater than 75%) were 94%, 71% and 78% for all branches, respectively. The calcification score for vessels with significant stenotic lesion (n = 48) was statistically higher (p less than 0.01) than that for vessels without stenotic lesion (n = 45). In conclusion, UFCT appears to be useful noninvasive screening examination for detecting CAD, although a prospective study in a large number of patients will be necessary to establish the value of this new method more reliably.
|Number of pages||7|
|Journal||Nippon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica|
|Publication status||Published - 1991 Nov 25|
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging