Evaluation of cerebral blood flow and metabolism in childhood moyamoya disease: an investigation into "re-build-up" on EEG by positron CT

Motonobu Kameyama, Reizo Shirane, Yuji Tsurumi, Akira Takahashi, Satoru Fujiwara, Jiro Suzuki, Masatoshi Ito, Tatsuo Ido

Research output: Contribution to journalArticlepeer-review

24 Citations (Scopus)

Abstract

The cerebral blood flow and cerebral metabolic rate of oxygen (CBF and CMRO2) of three cases of childhood moyamoya disease were examined by positron-emission-computed tomography for the purpose of investigating the mechanism of the "re-build-up" phenomenon on EEG. Decrease in both CBF and CMRO2 were observed following hyperventilation. However, dissociation between the decrease in CBF and CMRO2 was also observed. Arterial blood-gas analysis disclosed hypocapnea during hyperventilation and hypoxia following hyperventilation. These results clearly indicate that the re-build-up seen on EEG is the manifestation not only of ischemic hypoxia but also of hypoxic hypoxia characteristically seen in moyamoya disease.

Original languageEnglish
Pages (from-to)130-133
Number of pages4
JournalChild's Nervous System
Volume2
Issue number3
DOIs
Publication statusPublished - 1986 Sep

Keywords

  • Cerebral blood flow
  • Cerebral metabolism
  • EEG
  • Moyamoya disease
  • Positron CT
  • Re-build-up

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology

Fingerprint Dive into the research topics of 'Evaluation of cerebral blood flow and metabolism in childhood moyamoya disease: an investigation into "re-build-up" on EEG by positron CT'. Together they form a unique fingerprint.

Cite this