Evaluation of a cleaning process inside a microfluidic channel using a single-chip QCM array

Takashi Abe, Yousuke Itasaka, Hirokazu Kaji, Matsuhiko Nishizawa

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

This paper reports a cleaning method for sensor array inside a packaged micro-fluidic device and the evaluation method. A single-chip quartz-crystal microbalance (QCM) array was used as a model of sensor array since it can evaluate the cleaning process in real-time. By locally generating HBrO and Br - at a working electrode in the microfluidic device, gold electrode of the QCM was etched at an atomic layer level. Since the HBrO removes blocking agent on the electrode of QCM, it allows also site-specific immobilization of materials by introducing materials of interest into the device. This method is expected to use as a simple method for cleaning and surface modification of sensor array after assembling the microfluidic device.

Original languageEnglish
Title of host publicationProceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherChemical and Biological Microsystems Society
Pages1650-1652
Number of pages3
ISBN (Print)9780979806421
Publication statusPublished - 2009 Jan 1
Event13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009 - Jeju, Korea, Republic of
Duration: 2009 Nov 12009 Nov 5

Publication series

NameProceedings of Conference, MicroTAS 2009 - The 13th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Other

Other13th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2009
CountryKorea, Republic of
CityJeju
Period09/11/109/11/5

Keywords

  • Array
  • Cleaning
  • Microfluidic
  • QCM
  • Surface modification

ASJC Scopus subject areas

  • Chemical Engineering (miscellaneous)
  • Bioengineering

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