Erythema induratum of Bazin as a type of tuberculid

Yoko Kuramoto, Setsuya Aiba, Hachiro Tagami

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34 Citations (Scopus)


We report three cases of patients with erythema induratum of Bazin who showed extreme tuberculin hypersensitivity reactions and a good therapeutic response to isoniazid. In the first patient satellite lesions with epithelioid granuloma formation developed 3 weeks after injection of purified protein derivative. In the second patient a high fever developed 1 day after injection of purified protein derivative, and the third patient blistered at the injection site; the histopathologic pattern was similar to erythema multiforme. Immunohistologic study of the epithelioid granulomas demonstrated a predominance of Leu-1-bearing, Leu-3a-bearing, and human lymphocyte antigen-DR-expressing cells. We conclude that erythema induratum of Bazin represents a tuberculid caused by heightened delayed-type hypersensitivity to components of tubercle bacilli released from latent foci of infection.

Original languageEnglish
Pages (from-to)612-616
Number of pages5
JournalJournal of the American Academy of Dermatology
Issue number4
Publication statusPublished - 1990

ASJC Scopus subject areas

  • Dermatology


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