Eosinophilic heart disease with favorable courses: Report of two cases

N. Ono; Y. Shimizu; A. Kasai; T. Yamaguchi; M. Unno; H. Nishikawa; Y. Kakuta; T. Yabana; H. Uchida

Eosinophilic heart disease with favorable courses: Report of two cases

N. Ono, Y. Shimizu, A. Kasai, T. Yamaguchi, M. Unno, H. Nishikawa, Y. Kakuta, T. Yabana, H. Uchida

Research output: Contribution to journal › Article

Abstract

Two cases of eosinophilia-associated acute peri-myocarditis which coursed favorably are reported. Case 1 was a 47-year-old man whose ECG revealed QS, ST-T change, bundle branch block, and arrhythmias. Case 2 was a 30-year-old man whose ECG showed ST segment depression. The chest radiographs of both patients revealed enlarged hearts. Left ventriculography showed abnormal regional wall motion. Their endomyocardial biopsies revealed eosinophilic infiltration of the myocardium, but few eosinophils were degranulated. In Case 1, the development of eosinophilia preceded perimyocarditis and the eosinophilia continued even after the symptoms of peri-myocarditis were improved. In conclusion, it seems that eosinophilia did not have specific relation to the initial manifestation of the disease but that it occurred as a secondary reaction to peri-myocarditis of unknown etiology in these cases.

Original language	English
Pages (from-to)	171-181
Number of pages	11
Journal	Journal of cardiology
Volume	21
Issue number	1
Publication status	Published - 1991 Dec 1
Externally published	Yes

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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Ono, N., Shimizu, Y., Kasai, A., Yamaguchi, T., Unno, M., Nishikawa, H., Kakuta, Y., Yabana, T., & Uchida, H. (1991). Eosinophilic heart disease with favorable courses: Report of two cases. Journal of cardiology, 21(1), 171-181.

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abstract = "Two cases of eosinophilia-associated acute peri-myocarditis which coursed favorably are reported. Case 1 was a 47-year-old man whose ECG revealed QS, ST-T change, bundle branch block, and arrhythmias. Case 2 was a 30-year-old man whose ECG showed ST segment depression. The chest radiographs of both patients revealed enlarged hearts. Left ventriculography showed abnormal regional wall motion. Their endomyocardial biopsies revealed eosinophilic infiltration of the myocardium, but few eosinophils were degranulated. In Case 1, the development of eosinophilia preceded perimyocarditis and the eosinophilia continued even after the symptoms of peri-myocarditis were improved. In conclusion, it seems that eosinophilia did not have specific relation to the initial manifestation of the disease but that it occurred as a secondary reaction to peri-myocarditis of unknown etiology in these cases.",

author = "N. Ono and Y. Shimizu and A. Kasai and T. Yamaguchi and M. Unno and H. Nishikawa and Y. Kakuta and T. Yabana and H. Uchida",

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AU - Ono, N.

AU - Shimizu, Y.

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AU - Yamaguchi, T.

AU - Unno, M.

AU - Nishikawa, H.

AU - Kakuta, Y.

AU - Yabana, T.

AU - Uchida, H.

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AB - Two cases of eosinophilia-associated acute peri-myocarditis which coursed favorably are reported. Case 1 was a 47-year-old man whose ECG revealed QS, ST-T change, bundle branch block, and arrhythmias. Case 2 was a 30-year-old man whose ECG showed ST segment depression. The chest radiographs of both patients revealed enlarged hearts. Left ventriculography showed abnormal regional wall motion. Their endomyocardial biopsies revealed eosinophilic infiltration of the myocardium, but few eosinophils were degranulated. In Case 1, the development of eosinophilia preceded perimyocarditis and the eosinophilia continued even after the symptoms of peri-myocarditis were improved. In conclusion, it seems that eosinophilia did not have specific relation to the initial manifestation of the disease but that it occurred as a secondary reaction to peri-myocarditis of unknown etiology in these cases.

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