TY - JOUR
T1 - Eosinophilia associated with dobutamine allergy causes eosinophilic endomyocarditis confirmed by serial endomyocardial biopsies
AU - Funasako, Moritoshi
AU - Funada, Akira
AU - Kanzaki, Hideaki
AU - Takahama, Hiroyuki
AU - Amaki, Makoto
AU - Hasegawa, Takuya
AU - Ikeda, Yoshihiko
AU - Ishibashi-Ueda, Hatsue
AU - Anzai, Toshihisa
AU - Kitakaze, Masafumi
N1 - Funding Information:
The present study was supported by Intramural Research Fund (22-5-6) for Cardiovascular Disease of National Cerebral and Cardiovascular Center.
PY - 2012/12
Y1 - 2012/12
N2 - We report a case of eosinophilic endomyocarditis caused by eosinophilia due to dobutamine allergy and successfully treated by a short-term and medium-dose steroid administration. Serial endomyocardial biopsies were useful for early diagnosis and evaluation of the effect of the treatment. Eosinophilic endomyocarditis due to dobutamine allergy is a rare entity; however, because of the high utilization rate of dobutamine in patients with low output heart failure, it is important to recognize that additional deterioration of cardiac function caused by eosinophilic endomyocarditis makes prognosis poor and early intervention is necessary.< Learning objective: Eosinophilic endomyocarditis due to dobutamine allergy is a rare entity; however, because of the high utilization rate of dobutamine in patients with low output heart failure, it is important to recognize that additional deterioration of cardiac function caused by eosinophilic endomyocarditis makes their prognosis poor and early intervention is necessary. Serial endomyocardial biopsies were useful for early diagnosis and evaluation of the effect of the treatment.>.
AB - We report a case of eosinophilic endomyocarditis caused by eosinophilia due to dobutamine allergy and successfully treated by a short-term and medium-dose steroid administration. Serial endomyocardial biopsies were useful for early diagnosis and evaluation of the effect of the treatment. Eosinophilic endomyocarditis due to dobutamine allergy is a rare entity; however, because of the high utilization rate of dobutamine in patients with low output heart failure, it is important to recognize that additional deterioration of cardiac function caused by eosinophilic endomyocarditis makes prognosis poor and early intervention is necessary.< Learning objective: Eosinophilic endomyocarditis due to dobutamine allergy is a rare entity; however, because of the high utilization rate of dobutamine in patients with low output heart failure, it is important to recognize that additional deterioration of cardiac function caused by eosinophilic endomyocarditis makes their prognosis poor and early intervention is necessary. Serial endomyocardial biopsies were useful for early diagnosis and evaluation of the effect of the treatment.>.
KW - Biopsy
KW - Dobutamine
KW - Drug-induced lymphocyte stimulation test
KW - Eosinophilia
KW - Eosinophilic endomyocarditis
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U2 - 10.1016/j.jccase.2012.08.004
DO - 10.1016/j.jccase.2012.08.004
M3 - Article
AN - SCOPUS:84871761901
VL - 6
SP - e179-e182
JO - Journal of Cardiology Cases
JF - Journal of Cardiology Cases
SN - 1878-5409
IS - 6
ER -