Eosinophilia associated with dobutamine allergy causes eosinophilic endomyocarditis confirmed by serial endomyocardial biopsies

Moritoshi Funasako, Akira Funada, Hideaki Kanzaki, Hiroyuki Takahama, Makoto Amaki, Takuya Hasegawa, Yoshihiko Ikeda, Hatsue Ishibashi-Ueda, Toshihisa Anzai, Masafumi Kitakaze

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

We report a case of eosinophilic endomyocarditis caused by eosinophilia due to dobutamine allergy and successfully treated by a short-term and medium-dose steroid administration. Serial endomyocardial biopsies were useful for early diagnosis and evaluation of the effect of the treatment. Eosinophilic endomyocarditis due to dobutamine allergy is a rare entity; however, because of the high utilization rate of dobutamine in patients with low output heart failure, it is important to recognize that additional deterioration of cardiac function caused by eosinophilic endomyocarditis makes prognosis poor and early intervention is necessary.< Learning objective: Eosinophilic endomyocarditis due to dobutamine allergy is a rare entity; however, because of the high utilization rate of dobutamine in patients with low output heart failure, it is important to recognize that additional deterioration of cardiac function caused by eosinophilic endomyocarditis makes their prognosis poor and early intervention is necessary. Serial endomyocardial biopsies were useful for early diagnosis and evaluation of the effect of the treatment.>.

Original languageEnglish
Pages (from-to)e179-e182
JournalJournal of Cardiology Cases
Volume6
Issue number6
DOIs
Publication statusPublished - 2012 Dec
Externally publishedYes

Keywords

  • Biopsy
  • Dobutamine
  • Drug-induced lymphocyte stimulation test
  • Eosinophilia
  • Eosinophilic endomyocarditis

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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