Eosinophil and neutrophil production of leukotriene C4 and B4: Comparison of cells from asthmatic subjects and healthy donors

T. Aizawa; G. Tamura; Hiroshi Otsu; T. Takishima

Eosinophil and neutrophil production of leukotriene C₄ and B₄: Comparison of cells from asthmatic subjects and healthy donors

T. Aizawa, G. Tamura, Hiroshi Otsu, T. Takishima

ENG - Quantum Science and Energy Engineering

Research output: Contribution to journal › Article

25 Citations (Scopus)

Abstract

Production of LTC₄ and LTB₄ by eosinophils and neutrophils was compared between nine asymptomatic asthmatic subjects and eight health donors. We observed a statistically significant difference in LTC₄ generated by eosinophils, but not LTB₄ produced by neutrophils. These findings suggest a quantitative difference in eosinophils between asthmatic subjects and healthy donors.

Original language	English
Pages (from-to)	287-292
Number of pages	6
Journal	Annals of Allergy
Volume	64
Issue number	3
Publication status	Published - 1990 Jan 1

ASJC Scopus subject areas

Immunology and Allergy

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title = "Eosinophil and neutrophil production of leukotriene C4 and B4: Comparison of cells from asthmatic subjects and healthy donors",

abstract = "Production of LTC4 and LTB4 by eosinophils and neutrophils was compared between nine asymptomatic asthmatic subjects and eight health donors. We observed a statistically significant difference in LTC4 generated by eosinophils, but not LTB4 produced by neutrophils. These findings suggest a quantitative difference in eosinophils between asthmatic subjects and healthy donors.",

author = "T. Aizawa and G. Tamura and Hiroshi Otsu and T. Takishima",

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AU - Otsu, Hiroshi

AU - Takishima, T.

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AB - Production of LTC4 and LTB4 by eosinophils and neutrophils was compared between nine asymptomatic asthmatic subjects and eight health donors. We observed a statistically significant difference in LTC4 generated by eosinophils, but not LTB4 produced by neutrophils. These findings suggest a quantitative difference in eosinophils between asthmatic subjects and healthy donors.

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