Enzyme-based fabrication of physical DNA hydrogels: new materials and applications

Shogo Hamada, Dan Luo

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)


Advancements in DNA nanotechnology and nanobioengineering allowed the use of DNA as a generic material, as well as a genetic material. Among various DNA-based materials, DNA hydrogels achieve a DNA-based network at the bulk scale. Notably, a recently developed enzyme-based fabrication method established a route to synthesize physically crosslinked networks from DNA. This new class of DNA networks paved the way for creating different forms of DNA materials by utilizing the characteristics of a biofunctional polymer. This Focus Review provides a brief overview of the enzyme-based fabrication method of physical DNA hydrogels and discusses the latest developments in technology and their applications.

Original languageEnglish
Pages (from-to)891-898
Number of pages8
JournalPolymer Journal
Issue number8
Publication statusPublished - 2020 Aug 1
Externally publishedYes

ASJC Scopus subject areas

  • Polymers and Plastics
  • Materials Chemistry


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