Enhancement of surface plasmon resonance sensing for DNA hybridization using colloidal Au attached probe DNA

Akira Yamaguchi, Saulius Juodkazis, Shigeki Matsuo, Hiroaki Misawa

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

In this study, we demonstrate that the Au particle modified probe DNA monolayer can enhance the surface plasmon resonance (SPR) signal for measuring hybridization of unlabeled DNA molecules. The Au particles adsorbed on single stranded (ss)- and double stranded (ds)-DNA monolayers have different optical interaction with surface of Au thin film, and this difference induces the enhancement of the SPR signal.

Original languageEnglish
Pages (from-to)190-191
Number of pages2
JournalChemistry Letters
Issue number2
Publication statusPublished - 2002 Feb 5

ASJC Scopus subject areas

  • Chemistry(all)

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